ENSGALG00000009556


Gallus gallus
regulationPRICKLE1proteinzincnucleusdevelopmentionbindingfingerlim-typepetdomainneuraltubeclosureimportubiquitinationproteasomalubiquitin-dependentcatabolicprocessaortatranscriptiondna-templatedcoronaryvasculaturecanonicalwntsignalingpathwaycardiac

Features
Gene ID: ENSGALG00000009556
  
Biological name :PRICKLE1
  
Synonyms : PRICKLE1 / prickle planar cell polarity protein 1
  
Possible biological names infered from orthology : Prickle-like protein 1 / Q3U5C7 / Q96MT3
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 29649659
Gene end: 29708429
  
Corresponding Affymetrix probe sets: GgaAffx.6003.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050417
Ensembl peptide - ENSGALP00000015542
NCBI entrez gene - 417793     See in Manteia.
RefSeq - XM_015282435
RefSeq - XM_015282440
RefSeq - XM_416036
RefSeq - XM_015282428
RefSeq - XM_015282431
swissprot - F1P3B6
Ensembl - ENSGALG00000009556
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prickle1aENSDARG00000040649Danio rerio
 prickle1bENSDARG00000045694Danio rerio
 Q96MT3ENSG00000139174Homo sapiens
 Q3U5C7ENSMUSG00000036158Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRICKLE2 / prickle planar cell polarity protein 2 / Q7Z3G6* / Q80Y24*ENSGALG0000000733250
Q2TBC4* / Gm21981* / PRICKLE4* / AL365205.1* / prickle planar cell polarity protein 4*ENSGALG0000002826222
TES / Q90YH9 / Testin / Q9UGI8* / Gm4907* / Gm4985* / testin LIM domain protein* / testis derived transcript*ENSGALG0000003193415
LMCD1 / LIM and cysteine rich domains 1 / Q8VEE1* / Q9NZU5*ENSGALG0000000834912


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR010442  PET domain


Gene Ontology (GO)
anatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcatabolic processbiosynthetic processcell communicationcellular response to stimuluscellular developmental processanatomicalanatomical structure developmentmacromolecmacromolecule localizationestablishmestablishment of localizationcellular lcellular localizationnitrogen cnitrogen compound metabolic processcellular mcellular metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processcatabolic catabolic processbiosynthetbiosynthetic processcell commucell communicationcellular rcellular response to stimuluscellular dcellular developmental process
ion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0035904 aorta development IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0060976 coronary vasculature development IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:2000691 negative regulation of cardiac muscle cell myoblast differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Asymmetric localization of PCP proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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