ENSGALG00000009567


Gallus gallus

Features
Gene ID: ENSGALG00000009567
  
Biological name :TLL1
  
Synonyms : TLL1 / tolloid-like protein 1 precursor
  
Possible biological names infered from orthology : O43897 / tolloid-like / tolloid like 1
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 24224993
Gene end: 24358195
  
Corresponding Affymetrix probe sets: Gga.1789.1.S1_at (Chicken Array)   Gga.239.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015567
Ensembl peptide - ENSGALP00000061751
Ensembl peptide - ENSGALP00000056284
NCBI entrez gene - 395441     See in Manteia.
RefSeq - NM_204703
RefSeq - XM_015285274
RefSeq Peptide - NP_990034
swissprot - A0A1L1RSG5
swissprot - A0A1D5PTN6
swissprot - F1P398
Ensembl - ENSGALG00000009567
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tll1ENSDARG00000037429Danio rerio
 TLL1ENSG00000038295Homo sapiens
 Tll1ENSMUSG00000053626Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLL2 / tolloid like 2 / Q9WVM6* / Q9Y6L7* / Tolloid-like protein 2 *ENSGALG0000000551973
CUBN / cubilin / O60494* / Q9JLB4*ENSGALG0000000870429
CDCP2 / CUB domain containing protein 2 / Q5VXM1* / Q8BQH6*ENSGALG0000001075213
NETO2 / neuropilin and tolloid like 2 / Q8BNJ6* / Q8NC67* / Mus musculus neuropilin (NRP) and tolloid (TLL)-like 2 (Neto2), transcript variant 1, mRNA.*ENSGALG0000000407112
PCOLCE2 / procollagen C-endopeptidase enhancer 2 / Q8R4W6* / Q9UKZ9*ENSGALG0000000262311
NETO1 / neuropilin and tolloid like 1 / Q8R4I7* / Q8TDF5* / Neuropilin and tolloid-like protein 1 *ENSGALG000000411848
MFRP / membrane frizzled-related protein / Q8K480* / Q9BY79*ENSGALG000000329797


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR000859  CUB domain
 IPR001506  Peptidase M12A
 IPR001881  EGF-like calcium-binding domain
 IPR006026  Peptidase, metallopeptidase
 IPR013032  EGF-like, conserved site
 IPR015446  Bone morphogenetic protein 1/tolloid-like protein
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Collagen biosynthesis and modifying enzymes
Anchoring fibril formation
Crosslinking of collagen fibrils


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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