ENSGALG00000009791


Gallus gallus

Features
Gene ID: ENSGALG00000009791
  
Biological name :PROX1
  
Synonyms : prospero homeobox protein 1 / PROX1
  
Possible biological names infered from orthology : P48437 / prospero homeobox 1 / Q92786
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 21313970
Gene end: 21357168
  
Corresponding Affymetrix probe sets: Gga.2460.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058601
Ensembl peptide - ENSGALP00000015910
Ensembl peptide - ENSGALP00000046083
NCBI entrez gene - 395802     See in Manteia.
RefSeq - XM_015283622
RefSeq - NM_001005616
RefSeq - XM_015283620
RefSeq - XM_015283621
RefSeq Peptide - NP_001005616
swissprot - F1P568
swissprot - A0A1D5Q031
Ensembl - ENSGALG00000009791
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prox1aENSDARG00000055158Danio rerio
 PROX1ENSG00000117707Homo sapiens
 Prox1ENSMUSG00000010175Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PROX2* / Q3B8N5* / Q8BII1* / prospero homeobox 2* / Prospero homeobox protein 2 *ENSGALG0000002311314


Protein motifs (from Interpro)
Interpro ID Name
 IPR009057  Homeobox-like domain superfamily
 IPR023082  Homeo-prospero domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001709 cell fate determination IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0001945 lymph vessel development IEA
 biological_processGO:0001946 lymphangiogenesis IEA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0002089 lens morphogenesis in camera-type eye IEA
 biological_processGO:0002194 hepatocyte cell migration IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IEA
 biological_processGO:0021542 dentate gyrus development IEA
 biological_processGO:0021707 cerebellar granule cell differentiation IEA
 biological_processGO:0030240 skeletal muscle thin filament assembly IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0042752 regulation of circadian rhythm IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045071 negative regulation of viral genome replication IEA
 biological_processGO:0045446 endothelial cell differentiation IEA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046619 optic placode formation involved in camera-type eye formation IEA
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0048845 venous blood vessel morphogenesis IEA
 biological_processGO:0055005 ventricular cardiac myofibril assembly IEA
 biological_processGO:0055009 atrial cardiac muscle tissue morphogenesis IEA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IEA
 biological_processGO:0060214 endocardium formation IEA
 biological_processGO:0060298 positive regulation of sarcomere organization IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0060414 aorta smooth muscle tissue morphogenesis IEA
 biological_processGO:0060421 positive regulation of heart growth IEA
 biological_processGO:0060836 lymphatic endothelial cell differentiation IEA
 biological_processGO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment IEA
 biological_processGO:0061114 branching involved in pancreas morphogenesis IEA
 biological_processGO:0070309 lens fiber cell morphogenesis IEA
 biological_processGO:0070365 hepatocyte differentiation IEA
 biological_processGO:0070858 negative regulation of bile acid biosynthetic process IEA
 biological_processGO:0072574 hepatocyte proliferation IEA
 biological_processGO:0090425 acinar cell differentiation IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEA
 biological_processGO:1901978 positive regulation of cell cycle checkpoint IEA
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation IEA
 biological_processGO:2000979 positive regulation of forebrain neuron differentiation IEA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0016922 nuclear receptor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0050692 DBD domain binding IEA
 molecular_functionGO:0050693 LBD domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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