ENSGALG00000010866


Gallus gallus

Features
Gene ID: ENSGALG00000010866
  
Biological name :AREG
  
Synonyms : amphiregulin / AREG
  
Possible biological names infered from orthology : Mcub / P15514 / P31955
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 45060436
Gene end: 45066903
  
Corresponding Affymetrix probe sets: GgaAffx.6867.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017644
NCBI entrez gene - 428752     See in Manteia.
RefSeq - NM_001031537
RefSeq - XM_015276315
RefSeq Peptide - NP_001026708
swissprot - Q645M5
Ensembl - ENSGALG00000010866
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aregENSDARG00000076853Danio rerio
 AREGENSG00000109321Homo sapiens
 McubENSMUSG00000029378Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HBEGF / Q9W7C5 / Proheparin-binding EGF-like growth factor Heparin-binding EGF-like growth factor / Q06186* / Q99075* / heparin binding EGF like growth factor*ENSGALG0000000094922


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR013032  EGF-like, conserved site
 IPR015497  Epidermal growth factor receptor ligand


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060744 mammary gland branching involved in thelarche IEA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0060750 epithelial cell proliferation involved in mammary gland duct elongation IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr