ENSGALG00000011065


Gallus gallus
bindingSPRTNdnaproteinresponsetranslesionsynthesispolyubiquitinmodification-dependentsprt-likezincfingerrad-typeputativerepaircellulardamagestimulusuvregulationubiquitinationnucleusnucleoplasmnuclearspeckubiquitink-linkedpolh

Features
Gene ID: ENSGALG00000011065
  
Biological name :SPRTN
  
Synonyms : SprT-like N-terminal domain / SPRTN
  
Possible biological names infered from orthology : G3X912 / Q9H040 / SprT-like domain-containing protein Spartan
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 39895267
Gene end: 39898867
  
Corresponding Affymetrix probe sets: GgaAffx.6999.1.S1_at (Chicken Array)   GgaAffx.6999.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000017996
NCBI entrez gene - 421530     See in Manteia.
RefSeq - XM_419571
swissprot - E1BQ54
Ensembl - ENSGALG00000011065
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sprtnENSDARG00000104709Danio rerio
 SPRTNENSG00000010072Homo sapiens
 SprtnENSMUSG00000031986Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006640  SprT-like
 IPR006642  Zinc finger, Rad18-type putative


Gene Ontology (GO)
nitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusresponse to abiotic stimulusbiosynthetic processnitrogen compoundnitrogen compound metabolic processresponse to stresresponse to stresscellular metabolicellular metabolic processprimary metabolicprimary metabolic processorganic substanceorganic substance metabolic processcellular responsecellular response to stimulusresponse to abiotresponse to abiotic stimulusbiosynthetic procbiosynthetic process
organic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingprotein bindingprotein binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0019985 translesion synthesis IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IBA
 molecular_functionGO:0043130 ubiquitin binding IEA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Translesion Synthesis by POLH


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000734 RPA2 / RPA4* / Q13156* / P15927* / replication protein A2* / replication protein A4*  / complex / reaction
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / complex / reaction
 ENSGALG00000010700 RPA3 / replication protein A3 / P35244* / Q9CQ71* / Replication protein A 14 kDa subunit *  / complex / reaction
 ENSGALG00000029292 PCNA / Q9DEA3 / Proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000010317 POLH / DNA polymerase eta / Q9JJN0* / Q9Y253*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr