ENSGALG00000011286


Gallus gallus

Features
Gene ID: ENSGALG00000011286
  
Biological name :UBE2E1
  
Synonyms : UBE2E1 / ubiquitin conjugating enzyme E2 E1
  
Possible biological names infered from orthology : P51965 / P52482
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 37271244
Gene end: 37314446
  
Corresponding Affymetrix probe sets: Gga.17162.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018392
NCBI entrez gene - 420653     See in Manteia.
RefSeq - XM_004939408
RefSeq - XM_015281794
RefSeq - XM_004939409
RefSeq - XM_015281793
swissprot - F1P120
Ensembl - ENSGALG00000011286
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl15ENSDARG00000116649Danio rerio
 ube2e2ENSDARG00000034670Danio rerio
 P51965ENSG00000170142Homo sapiens
 P52482ENSMUSG00000021774Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE2E2 / ubiquitin conjugating enzyme E2 E2 / Q91W82* / Q96LR5*ENSGALG0000003359385
UBE2E3 / ubiquitin conjugating enzyme E2 E3 / P52483* / Q969T4*ENSGALG0000002079383
UBE2D3ENSGALG0000001231148
UBE2D2 / ubiquitin conjugating enzyme E2 D2 / P62838* / P62837* / Ube2d2a* / ubiquitin-conjugating enzyme E2D 2A*ENSGALG0000003812848
UBE2D1 / ubiquitin conjugating enzyme E2 D1 / P51668* / P61080*ENSGALG0000002121346
UBE2L3 / P68037* / ubiquitin-conjugating enzyme E2L 3*ENSGALG0000003673927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0010390 histone monoubiquitination IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032020 ISG15-protein conjugation IEA
 biological_processGO:0033523 histone H2B ubiquitination IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042296 ISG15 transferase activity IEA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex
 ENSGALG00000028935 BCL10 / B cell CLL/lymphoma 10 / O95999* / Q9Z0H7* / B-cell lymphoma/leukemia 10 *  / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex






 

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