ENSGALG00000014751


Gallus gallus
ADAMTS6peptidasembmetallopeptidaseactivitythrombospondintype-tsprepeatadamreprolysinpropeptideadam-tsspacercatalyticdomainsuperfamilycardiacseptumproteolysisheartaortacoronaryvasculaturemetalloendopeptidasemetalionbindingo-glycosylation

Features
Gene ID: ENSGALG00000014751
  
Biological name :ADAMTS6
  
Synonyms : ADAM metallopeptidase with thrombospondin type 1 motif 6 / ADAMTS6
  
Possible biological names infered from orthology : a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 / Q9UKP5
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 20383073
Gene end: 20519927
  
Corresponding Affymetrix probe sets: Gga.13452.1.S1_at (Chicken Array)   GgaAffx.9368.1.S1_at (Chicken Array)   GgaAffx.9368.2.S1_at (Chicken Array)   GgaAffx.9368.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023740
Ensembl peptide - ENSGALP00000045100
NCBI entrez gene - 427160     See in Manteia.
RefSeq - XM_424749
swissprot - A0A1D5NXK3
swissprot - E1C0H0
Ensembl - ENSGALG00000014751
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamts6ENSDARG00000041982Danio rerio
 Q9UKP5ENSG00000049192Homo sapiens
 Adamts6ENSMUSG00000046169Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAMTS10 / ADAM metallopeptidase with thrombospondin type 1 motif 10 / P58459* / Q9H324* / Mus musculus a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 ...ENSGALG0000003315770
ADAMTS18 / ADAM metallopeptidase with thrombospondin type 1 motif 18 / Q4VC17* / Q8TE60* / A disintegrin and metalloproteinase with thrombospondin motifs 18 *ENSGALG0000000534742
ADAMTS17 / ADAM metallopeptidase with thrombospondin type 1 motif 17 / Q8TE56* / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17*ENSGALG0000003868836
ADAMTS19 / ADAM metallopeptidase with thrombospondin type 1 motif 19 / P59509* / Q8TE59* / A disintegrin and metalloproteinase with thrombospondin motifs 19 *ENSGALG0000000015135
ADAMTS3 / ADAM metallopeptidase with thrombospondin type 1 motif 3 / O15072* / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3*ENSGALG0000001162334
ADAMTS14 / ADAM metallopeptidase with thrombospondin type 1 motif 14 / Q8WXS8* / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14*ENSGALG0000003921933
ADAMTS2 / ADAM metallopeptidase with thrombospondin type 1 motif 2 / O95450* / Q8C9W3* / A disintegrin and metalloproteinase with thrombospondin motifs 2 *ENSGALG0000003297432


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR002870  Peptidase M12B, propeptide
 IPR010294  ADAM-TS Spacer 1
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
anatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentanatomical structure developmentnitrogen compound metabolic processnitrogen compound metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic processorganic substance metabolic process
catalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteinhydrolase activityion bindingcatalytic activity, acting on a proteincatalytic activity, acting on a proteinhydrolase activityhydrolase activityion bindingion binding
TypeGO IDTermEv.Code
 biological_processGO:0003279 cardiac septum development IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0035904 aorta development IEA
 biological_processGO:0060976 coronary vasculature development IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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