ENSGALG00000015032


Gallus gallus

Features
Gene ID: ENSGALG00000015032
  
Biological name :CD274
  
Synonyms : CD274 / CD274 molecule
  
Possible biological names infered from orthology : CD274 antigen / Q9EP73 / Q9NZQ7
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 27673716
Gene end: 27679160
  
Corresponding Affymetrix probe sets: GgaAffx.24574.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024196
NCBI entrez gene - 427224     See in Manteia.
RefSeq - XM_015280141
swissprot - E1C153
Ensembl - ENSGALG00000015032
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-241b2.5ENSDARG00000100899Danio rerio
 CD274ENSG00000120217Homo sapiens
 Cd274ENSMUSG00000016496Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDCD1LG2 / programmed cell death 1 ligand 2 / Q9BQ51* / Q9WUL5*ENSGALG0000003179433


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0031295 T cell costimulation IEA
 biological_processGO:0032689 negative regulation of interferon-gamma production IEA
 biological_processGO:0032693 negative regulation of interleukin-10 production IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0046007 negative regulation of activated T cell proliferation IEA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production IEA
 biological_processGO:1905404 positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process IEA
 biological_processGO:2001181 positive regulation of interleukin-10 secretion IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome IEA


Pathways (from Reactome)
Pathway description
PD-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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