ENSGALG00000015377


Gallus gallus
regulationPHLDB2cytoskeletonassemblydomainmicrotubuleorganizationfocaladhesionmembranepleckstrinhomologyph-likesuperfamilygastrulationepithelialmesenchymaltransitionestablishmentproteinlocalizationstressfiberwoundhealingspreadingepidermalcellsbasementinvolvedembryonic

Features
Gene ID: ENSGALG00000015377
  
Biological name :PHLDB2
  
Synonyms : PHLDB2 / pleckstrin homology like domain family B member 2
  
Possible biological names infered from orthology : Q86SQ0 / Q8K1N2
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 88509484
Gene end: 88552963
  
Corresponding Affymetrix probe sets: Gga.13077.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024765
NCBI entrez gene - 418418     See in Manteia.
RefSeq - XM_015297598
RefSeq - XM_015297602
RefSeq - XM_015297607
RefSeq - XM_015297617
RefSeq - XM_015297628
RefSeq - XM_015297639
RefSeq - XM_015297646
RefSeq - XM_015297649
RefSeq - XM_015297657
RefSeq - XM_015297661
RefSeq - XM_015297663
RefSeq - XM_015297596
swissprot - E1C7W8
Ensembl - ENSGALG00000015377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phldb2aENSDARG00000079889Danio rerio
 phldb2bENSDARG00000074843Danio rerio
 PHLDB2ENSG00000144824Homo sapiens
 Phldb2ENSMUSG00000033149Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PHLDB1 / pleckstrin homology like domain family B member 1 / Q6PDH0* / Q86UU1*ENSGALG0000004003047


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
cellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular component organizationmicrotubule-based processanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesisactin filament-based processcell adhesionresponse to stressresponse to external stimuluslocalization of cellmovement of cell or subcellular componentcellular ccellular component organizationmicrotubulmicrotubule-based processanatomicalanatomical structure developmentcellular dcellular developmental processmacromolecmacromolecule localizationestablishmestablishment of localizationcellular ccellular component biogenesisactin filaactin filament-based processcell adhescell adhesionresponse tresponse to stressresponse tresponse to external stimuluslocalizatilocalization of cellmovement omovement of cell or subcellular component
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellmembranecell junctionorganellecellcellmembranemembranecell junctioncell junctionorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0010470 regulation of gastrulation IEA
 biological_processGO:0010717 regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:0051497 negative regulation of stress fiber assembly IEA
 biological_processGO:0051895 negative regulation of focal adhesion assembly IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:1903690 negative regulation of wound healing, spreading of epidermal cells IEA
 biological_processGO:1904261 positive regulation of basement membrane assembly involved in embryonic body morphogenesis IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 cellular_componentGO:0045180 basal cortex IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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