ENSGALG00000015635


Gallus gallus
bindingHTTregulationhuntingtingolgiproteintransportchannelactivityapoptoticvesiclecytoplasmarmadillo-likehelicalarmadillo-typefoldmiddle-repeatfamilyestablishmentmitoticspindleorientationretrogradevesicle-mediatederorganizationinositol-trisphosphate-sensitivecalcium-releasedestabilizationvocal

Features
Gene ID: ENSGALG00000015635
  
Biological name :HTT
  
Synonyms : HTT / huntingtin
  
Possible biological names infered from orthology : P42858
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 82710300
Gene end: 82783954
  
Corresponding Affymetrix probe sets: Gga.15073.1.S1_at (Chicken Array)   GgaAffx.9960.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025163
NCBI entrez gene - 422878     See in Manteia.
RefSeq - XM_004936202
RefSeq - XM_420822
swissprot - E1BZK0
Ensembl - ENSGALG00000015635
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 httENSDARG00000052866Danio rerio
 HTTENSG00000197386Homo sapiens
 HttENSMUSG00000029104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000091  Huntingtin
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024613  Huntingtin, middle-repeat
 IPR028426  Huntingtin family


Gene Ontology (GO)
cellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellular component organizationestablishment of localizationcell cyclecellular localizationestablishment or maintenance of cell polaritymicrotubule-based processcell communicationregulation of biological qualityregulation of molecular functioncellular response to stimulusresponse to external stimulussystem processresponse to abiotic stimuluscell deathnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular component biogenesismovement of cell or subcellular componentanatomical structure developmentcatabolic processprocess utilizing autophagic mechanismcellulcellular component organizationestablestablishment of localizationcell ccell cyclecellulcellular localizationestablestablishment or maintenance of cell polaritymicrotmicrotubule-based processcell ccell communicationregularegulation of biological qualityregularegulation of molecular functioncellulcellular response to stimulusresponresponse to external stimulussystemsystem processresponresponse to abiotic stimuluscell dcell deathnitrognitrogen compound metabolic processcellulcellular metabolic processprimarprimary metabolic processorganiorganic substance metabolic processcellulcellular component biogenesismovememovement of cell or subcellular componentanatomanatomical structure developmentcatabocatabolic processprocesprocess utilizing autophagic mechanism
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellorganellemembrane-enclosed lumenmembraneprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0042297 vocal learning IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0045724 positive regulation of cilium assembly IEA
 biological_processGO:0047496 vesicle transport along microtubule IEA
 biological_processGO:0048513 animal organ development IBA
 biological_processGO:1903599 positive regulation of autophagy of mitochondrion IEA
 biological_processGO:1904504 positive regulation of lipophagy IEA
 biological_processGO:1905337 positive regulation of aggrephagy IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016234 inclusion body IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0005522 profilin binding IEA
 molecular_functionGO:0008134 transcription factor binding IBA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0034452 dynactin binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0045505 dynein intermediate chain binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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