ENSGALG00000015884


Gallus gallus
chromosomeregulationMIS18Ayippeemiscereblonsegregationcenp-acontainingnucleosomeassemblydnamethylationproteintargetingmitochondrioncentromericregionchromatinnucleuscytosolmetalionbindingdepositionnewcenpa-containingnucleosomescentromere

Features
Gene ID: ENSGALG00000015884
  
Biological name :MIS18A
  
Synonyms : MIS18A / MIS18 kinetochore protein A
  
Possible biological names infered from orthology : Protein Mis18-alpha / Q9CZJ6 / Q9NYP9
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 104878056
Gene end: 104881365
  
Corresponding Affymetrix probe sets: Gga.12965.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025557
Ensembl peptide - ENSGALP00000047570
NCBI entrez gene - 418494     See in Manteia.
RefSeq - XM_416702
RefSeq - XM_015299740
swissprot - E1BQA3
swissprot - A0A1D5P4G2
Ensembl - ENSGALG00000015884
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mis18aENSDARG00000035333Danio rerio
 MIS18AENSG00000159055Homo sapiens
 Mis18aENSMUSG00000022978Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004910  Yippee/Mis18/Cereblon


Gene Ontology (GO)
chromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome segregationcellular component organizationcellular component biogenesisnitrogen compound metabolic processmethylationcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationchromosome schromosome segregationcellular comcellular component organizationcellular comcellular component biogenesisnitrogen comnitrogen compound metabolic processmethylationmethylationcellular metcellular metabolic processprimary metaprimary metabolic processorganic subsorganic substance metabolic processmacromoleculmacromolecule localizationestablishmenestablishment of localizationcellular loccellular localization
ion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion bindingion binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0034080 CENP-A containing nucleosome assembly IEA
 biological_processGO:0044030 regulation of DNA methylation IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000785 chromatin IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deposition of new CENPA-containing nucleosomes at the centromere


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008579 OIP5 / Opa interacting protein 5 / A2AQ14* / O43482* / Protein Mis18-beta *  / complex
 ENSGALG00000042491 P62801 / Histone H4   / complex
 ENSGALG00000037735 CENPA / histone H3-like centromeric protein A / O35216* / P49450* / centromere protein A*  / complex






 

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