ENSGALG00000016174


Gallus gallus
membraneLMBRD1insulinreceptorregulationproteinsignalingblmbr-likeinternalizationglucoseimportpathwaykinaselysosomeplasmaintegralcomponentclathrin-coatedendocyticvesiclebindingcobalamincblvitamintransportmetabolism

Features
Gene ID: ENSGALG00000016174
  
Biological name :LMBRD1
  
Synonyms : LMBRD1 / probable lysosomal cobalamin transporter
  
Possible biological names infered from orthology : LMBR1 domain containing 1 / Q8K0B2 / Q9NUN5
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 83383540
Gene end: 83449168
  
Corresponding Affymetrix probe sets: GgaAffx.10325.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047100
Ensembl peptide - ENSGALP00000031013
NCBI entrez gene - 421874     See in Manteia.
RefSeq - XM_015284746
RefSeq - NM_001006413
RefSeq Peptide - NP_001006413
swissprot - A0A1D5P346
swissprot - F1NWK3
Ensembl - ENSGALG00000016174
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lmbrd1ENSDARG00000104223Danio rerio
 LMBRD1ENSG00000168216Homo sapiens
 Lmbrd1ENSMUSG00000073725Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006876  LMBR1-like membrane protein


Gene Ontology (GO)
cellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic processestablishment of localizationorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular metabolic pcellular metabolic processestablishment of locestablishment of localizationorganic substance meorganic substance metabolic processcell communicationcell communicationresponse to endogenoresponse to endogenous stimulusresponse to chemicalresponse to chemicalcellular response tocellular response to stimulus
protein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein-containing complex bindingprotein bindingprotein bindingprotein-containing complex bindingprotein-containing complex binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0038016 insulin receptor internalization IEA
 biological_processGO:0046325 negative regulation of glucose import IEA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045334 clathrin-coated endocytic vesicle IEA
 molecular_functionGO:0005158 insulin receptor binding IEA


Pathways (from Reactome)
Pathway description
Cobalamin (Cbl, vitamin B12) transport and metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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