ENSGALG00000016313


Gallus gallus

Features
Gene ID: ENSGALG00000016313
  
Biological name :GCLC
  
Synonyms : GCLC / glutamate-cysteine ligase catalytic subunit
  
Possible biological names infered from orthology : P48506 / P97494
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 88537101
Gene end: 88568136
  
Corresponding Affymetrix probe sets: Gga.10006.1.S1_at (Chicken Array)   GgaAffx.24934.1.S1_at (Chicken Array)   GgaAffx.24934.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000026270
NCBI entrez gene - 421894     See in Manteia.
RefSeq - XM_419910
swissprot - F1NQZ9
Ensembl - ENSGALG00000016313
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gclcENSDARG00000013095Danio rerio
 GCLCENSG00000001084Homo sapiens
 GclcENSMUSG00000032350Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004308  Glutamate-cysteine ligase catalytic subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006534 cysteine metabolic process IEA
 biological_processGO:0006536 glutamate metabolic process IEA
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0006750 glutathione biosynthetic process IBA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0008637 apoptotic mitochondrial changes IEA
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0009410 response to xenobiotic stimulus IEA
 biological_processGO:0009725 response to hormone IEA
 biological_processGO:0019852 L-ascorbic acid metabolic process IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0046685 response to arsenic-containing substance IEA
 biological_processGO:0050880 regulation of blood vessel size IEA
 biological_processGO:0051900 regulation of mitochondrial depolarization IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0017109 glutamate-cysteine ligase complex IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004357 glutamate-cysteine ligase activity IBA
 molecular_functionGO:0016595 glutamate binding IEA
 molecular_functionGO:0043531 ADP binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0050662 coenzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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