ENSGALG00000016332


Gallus gallus

Features
Gene ID: ENSGALG00000016332
  
Biological name :MCPH1
  
Synonyms : MCPH1 / microcephalin 1
  
Possible biological names infered from orthology : Microcephalin / Q7TT79 / Q8NEM0
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 88911018
Gene end: 89032445
  
Corresponding Affymetrix probe sets: Gga.10899.1.S1_at (Chicken Array)   GgaAffx.24937.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000030991
Ensembl peptide - ENSGALP00000062232
Ensembl peptide - ENSGALP00000062079
Ensembl peptide - ENSGALP00000056746
NCBI entrez gene - 100125976     See in Manteia.
RefSeq - NM_001105319
RefSeq Peptide - NP_001098789
swissprot - E1C964
swissprot - A6MCV0
swissprot - A0A1L1RTU2
Ensembl - ENSGALG00000016332
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcph1ENSDARG00000058372Danio rerio
 MCPH1ENSG00000147316Homo sapiens
 Mcph1ENSMUSG00000039842Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR022047  Microcephalin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000132 establishment of mitotic spindle orientation IEA
 biological_processGO:0000724 double-strand break repair via homologous recombination TAS
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0043549 regulation of kinase activity IEA
 biological_processGO:0046605 regulation of centrosome cycle IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0060623 regulation of chromosome condensation IEA
 biological_processGO:0071539 protein localization to centrosome IEA
 biological_processGO:0071850 mitotic cell cycle arrest IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Condensation of Prophase Chromosomes
Recruitment of repair and signaling proteins to double-strand breaks


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004701 SET / Q01105* / Q9EQU5* / SETSIP* / P0DME0* / Protein SET * / SET-like protein* / SET nuclear proto-oncogene*  / complex / reaction






 

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contact: otassy@igbmc.fr