ENSGALG00000016370


Gallus gallus

Features
Gene ID: ENSGALG00000016370
  
Biological name :TPO
  
Synonyms : thyroid peroxidase / TPO
  
Possible biological names infered from orthology : P07202 / P35419
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 93135658
Gene end: 93174800
  
Corresponding Affymetrix probe sets: GgaAffx.10481.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000026355
NCBI entrez gene - 776120     See in Manteia.
RefSeq - XM_015284944
swissprot - F1NN54
Ensembl - ENSGALG00000016370
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TPOENSG00000115705Homo sapiens
 TpoENSMUSG00000020673Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPX* / MPO* / P49290* / P05164* / P11247* / P11678* / myeloperoxidase* / eosinophil peroxidase* / Myeloperoxidase Myeloperoxidase light chain Myeloperoxidase heavy chain* / Eosinophil perox...ENSGALG0000004325437
PXDN / peroxidasin / Q3UQ28* / Q92626* / Peroxidasin homolog *ENSGALG0000001637736
LPO* / P22079* / lactoperoxidase*ENSGALG0000003955436
ENSGALG0000003683835


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000436  Sushi/SCR/CCP domain
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR010255  Haem peroxidase
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR019791  Haem peroxidase, animal type
 IPR029589  Thyroid peroxidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006590 thyroid hormone generation IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0035162 embryonic hemopoiesis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004447 iodide peroxidase activity IEA
 molecular_functionGO:0004601 peroxidase activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
Thyroxine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr