ENSGALG00000016554


Gallus gallus
activityACE2regulationcellmembranepeptidasepeptidyl-dipeptidasereceptorhostcardiacextracellularmcollectrindomainangiotensin-mediateddrinkingbehaviorsystemicarterialbloodpressurerenin-angiotensinproteolysistryptophantransportbiosyntheticprocessviralentryreceptor-mediatedvirion

Features
Gene ID: ENSGALG00000016554
  
Biological name :ACE2
  
Synonyms : ACE2 / angiotensin I converting enzyme 2
  
Possible biological names infered from orthology : angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 / Q8R0I0 / Q9BYF1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 121938421
Gene end: 121960170
  
Corresponding Affymetrix probe sets: Gga.11350.1.S1_at (Chicken Array)   Gga.11350.2.S1_at (Chicken Array)   Gga.11350.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000026662
NCBI entrez gene - 418623     See in Manteia.
RefSeq - XM_416822
swissprot - F1NHR4
Ensembl - ENSGALG00000016554
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ace2ENSDARG00000016918Danio rerio
 ACE2ENSG00000130234Homo sapiens
 Ace2ENSMUSG00000015405Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACE / Ace3* / D0G895* / P12821* / P09470* / AC113554.1* / angiotensin I converting enzyme* / angiotensin I converting enzyme (peptidyl-dipeptidase A) 3* / angiotensin I converting enzyme (p...ENSGALG0000000049833
CLTRN / collectrin, amino acid transport regulator / Q9ESG4* / Q9HBJ8* / Tmem27* / Collectrin *ENSGALG000000291686


Protein motifs (from Interpro)
Interpro ID Name
 IPR001548  Peptidase M2, peptidyl-dipeptidase A
 IPR031588  Collectrin domain


Gene Ontology (GO)
feeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding behaviorregulation of biological qualitysystem processnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationbiosynthetic processcellular metabolic processinterspecies interaction between organismscellular component organizationcellular component biogenesismulticellular organismal signalingfeeding befeeding behaviorregulationregulation of biological qualitysystem prosystem processnitrogen cnitrogen compound metabolic processprimary meprimary metabolic processorganic suorganic substance metabolic processestablishmestablishment of localizationbiosynthetbiosynthetic processcellular mcellular metabolic processinterspeciinterspecies interaction between organismscellular ccellular component organizationcellular ccellular component biogenesismulticellumulticellular organismal signaling
virus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activitycatalytic activity, acting on a proteinhydrolase activityion bindingvirus receptor activityvirus receptor activitycatalytic activity, acting on a procatalytic activity, acting on a proteinhydrolase activityhydrolase activityion bindingion binding
extracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regionextracellular regioncellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0003051 angiotensin-mediated drinking behavior IEA
 biological_processGO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0015827 tryptophan transport IEA
 biological_processGO:0032800 receptor biosynthetic process IEA
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0046813 receptor-mediated virion attachment to host cell IEA
 biological_processGO:0060452 positive regulation of cardiac muscle contraction IEA
 biological_processGO:1903598 positive regulation of gap junction assembly IEA
 biological_processGO:1903779 regulation of cardiac conduction IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001618 virus receptor activity IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004180 carboxypeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008241 peptidyl-dipeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011117 AGT / angiotensinogen / P01019*  / reaction






 

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