ENSGALG00000016680


Gallus gallus

Features
Gene ID: ENSGALG00000016680
  
Biological name :TFAP2B
  
Synonyms : TFAP2B / transcription factor AP-2-beta
  
Possible biological names infered from orthology : Q61313 / Q92481
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 108690400
Gene end: 108715816
  
Corresponding Affymetrix probe sets: Gga.9289.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043765
Ensembl peptide - ENSGALP00000026865
NCBI entrez gene - 395713     See in Manteia.
RefSeq - XM_015285086
RefSeq - NM_204895
RefSeq - XM_015285085
RefSeq Peptide - NP_990226
swissprot - F6U0N4
swissprot - A0A1D5NTV8
Ensembl - ENSGALG00000016680
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfap2bENSDARG00000012667Danio rerio
 Q92481ENSG00000008196Homo sapiens
 Q61313ENSMUSG00000025927Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TFAP2A / transcription factor AP-2-alpha / P05549*ENSGALG0000001277566
TFAP2E / transcription factor AP-2 epsilon / Q6VUC0* / Q6VUP9*ENSGALG0000003949763
TFAP2C / transcription factor AP-2 gamma / Q61312* / Q92754*ENSGALG0000000769060
TFAP2D / transcription factor AP-2-delta / Q7Z6R9* / Q91ZK0*ENSGALG0000001984247


Protein motifs (from Interpro)
Interpro ID Name
 IPR004979  Transcription factor AP-2
 IPR008122  Transcription factor AP-2 beta
 IPR013854  Transcription factor AP-2, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0003091 renal water homeostasis IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007423 sensory organ development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010842 retina layer formation IEA
 biological_processGO:0010960 magnesium ion homeostasis IEA
 biological_processGO:0030510 regulation of BMP signaling pathway IEA
 biological_processGO:0035136 forelimb morphogenesis IEA
 biological_processGO:0035137 hindlimb morphogenesis IEA
 biological_processGO:0035810 positive regulation of urine volume IEA
 biological_processGO:0035909 aorta morphogenesis IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048485 sympathetic nervous system development IEA
 biological_processGO:0048856 anatomical structure development IBA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0055062 phosphate ion homeostasis IEA
 biological_processGO:0055074 calcium ion homeostasis IEA
 biological_processGO:0055075 potassium ion homeostasis IEA
 biological_processGO:0055078 sodium ion homeostasis IEA
 biological_processGO:0072017 distal tubule development IEA
 biological_processGO:0072044 collecting duct development IEA
 biological_processGO:0072210 metanephric nephron development IEA
 biological_processGO:0097070 ductus arteriosus closure IEA
 biological_processGO:0097275 cellular ammonia homeostasis IEA
 biological_processGO:0097276 cellular creatinine homeostasis IEA
 biological_processGO:0097277 cellular urea homeostasis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Activation of the TFAP2 (AP-2) family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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