ENSGALG00000021272


Gallus gallus
sodiumcardiacSCN2Bmusclechannelcellmembraneregulationactionpotentialactivityimmunoglobulinimmunoglobulin-likedomainiontransmembranecontractiondepolarizationinvolvedvoltage-gatedmyelinpprotein-relatedsubtypev-setfoldsubunitbeta-transportatrialheart

Features
Gene ID: ENSGALG00000021272
  
Biological name :SCN2B
  
Synonyms : SCN2B / sodium voltage-gated channel beta subunit 2
  
Possible biological names infered from orthology : O60939 / Q56A07 / Sodium channel subunit beta-2
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 5425639
Gene end: 5428446
  
Corresponding Affymetrix probe sets: GgaAffx.22242.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000033652
NCBI entrez gene - 419776     See in Manteia.
RefSeq - XM_417914
swissprot - E1BXH9
Ensembl - ENSGALG00000021272
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scn2bENSDARG00000101713Danio rerio
 SCN2BENSG00000149575Homo sapiens
 Scn2bENSMUSG00000070304Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCN4B / sodium voltage-gated channel beta subunit 4 / Q7M729* / Q8IWT1* / Sodium channel subunit beta-4 *ENSGALG0000000740925


Protein motifs (from Interpro)
Interpro ID Name
 IPR000920  Myelin P0 protein-related
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR029873  Sodium channel subunit beta-2


Gene Ontology (GO)
establishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of localizationsystem processregulation of biological qualitymovement of cell or subcellular componentactin filament-based processmulticellular organismal signalingregulation of molecular functionestablishment of locestablishment of localizationsystem processsystem processregulation of biologregulation of biological qualitymovement of cell or movement of cell or subcellular componentactin filament-basedactin filament-based processmulticellular organimulticellular organismal signalingregulation of molecuregulation of molecular function
channel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitytransmembrane transporter activitychannel regulator activitychannel regulator activitytransmembrane transporter activitytransmembrane transporter activity
cellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0060371 regulation of atrial cardiac muscle cell membrane depolarization IEA
 biological_processGO:0086002 cardiac muscle cell action potential involved in contraction IEA
 biological_processGO:0086012 membrane depolarization during cardiac muscle cell action potential IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:2000649 regulation of sodium ion transmembrane transporter activity IEA
 cellular_componentGO:0001518 voltage-gated sodium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0017080 sodium channel regulator activity IEA
 molecular_functionGO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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