ENSGALG00000024024


Gallus gallus

Features
Gene ID: ENSGALG00000024024
  
Biological name :TGFA
  
Synonyms : TGFA / transforming growth factor alpha
  
Possible biological names infered from orthology : P01135 / P48030
  
Species: Gallus gallus
  
Chr. number: 22
Strand: -1
Band:
Gene start: 3594207
Gene end: 3607707
  
Corresponding Affymetrix probe sets: GgaAffx.21846.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039726
Ensembl peptide - ENSGALP00000047237
swissprot - A0A1D5P3I2
swissprot - F1NYM9
Ensembl - ENSGALG00000024024
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tgfaENSDARG00000053939Danio rerio
 TGFAENSG00000163235Homo sapiens
 TgfaENSMUSG00000029999Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BTC / probetacellulin precursor / P35070* / Q05928* / betacellulin* / Probetacellulin Betacellulin*ENSGALG0000002860821


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR013032  EGF-like, conserved site
 IPR015497  Epidermal growth factor receptor ligand


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IBA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0072574 hepatocyte proliferation IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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