ENSGALG00000026557


Gallus gallus

Features
Gene ID: ENSGALG00000026557
  
Biological name :PGF
  
Synonyms : PGF / placental growth factor
  
Possible biological names infered from orthology : P49763 / P49764
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 38158264
Gene end: 38162063
  
Corresponding Affymetrix probe sets: GgaAffx.25296.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042015
swissprot - R4GIS1
Ensembl - ENSGALG00000026557
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01077555.1ENSDARG00000115359Danio rerio
 pgfbENSDARG00000076767Danio rerio
 PGFENSG00000119630Homo sapiens
 PgfENSMUSG00000004791Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VEGFA / P67964 / Vascular endothelial growth factor A / P15692* / Q00731*ENSGALG0000001029047


Protein motifs (from Interpro)
Interpro ID Name
 IPR000072  PDGF/VEGF domain
 IPR023581  Platelet-derived growth factor, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IBA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0001666 response to hypoxia IBA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0045766 positive regulation of angiogenesis IBA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway IBA
 biological_processGO:0050930 induction of positive chemotaxis IBA
 biological_processGO:0060688 regulation of morphogenesis of a branching structure IEA
 biological_processGO:0060754 positive regulation of mast cell chemotaxis IBA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005172 vascular endothelial growth factor receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
VEGF ligand-receptor interactions
VEGF binds to VEGFR leading to receptor dimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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