ENSGALG00000027262


Gallus gallus
proteinkinaseCAB39activityregulationphosphorylationserinethreoninesignaltransductionintracellularactivatorarmadillo-likehelicalmo-likearmadillo-typefoldpeptidyl-threoninepeptidyl-serineactivationbindingenergydependentmtorlkb-ampkneutrophildegranulation

Features
Gene ID: ENSGALG00000027262
  
Biological name :CAB39
  
Synonyms : CAB39 / calcium binding protein 39
  
Possible biological names infered from orthology : Mus musculus calcium binding protein 39 (Cab39), transcript variant 3, mRNA. / Q06138 / Q9Y376
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 5419310
Gene end: 5452363
  
Corresponding Affymetrix probe sets: Gga.5476.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041816
Ensembl peptide - ENSGALP00000057354
NCBI entrez gene - 424830     See in Manteia.
RefSeq - XM_015277058
RefSeq - XM_003641738
RefSeq - XM_004937029
swissprot - R4GI86
Ensembl - ENSGALG00000027262
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cab39ENSDARG00000043451Danio rerio
 CAB39ENSG00000135932Homo sapiens
 Cab39ENSMUSG00000036707Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAB39L / calcium binding protein 39 like / Q9DB16* / Q9H9S4*ENSGALG0000001700581


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR013878  Mo25-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusregulation of molecular functionnitrogen compound menitrogen compound metabolic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processcell communicationcell communicationcellular response tocellular response to stimulusregulation of molecuregulation of molecular function
catalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a proteintransferase activityprotein bindingenzyme regulator activitycatalytic activity, acting on a procatalytic activity, acting on a proteintransferase activitytransferase activityprotein bindingprotein bindingenzyme regulator activityenzyme regulator activity
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0030295 protein kinase activator activity IEA
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity IEA


Pathways (from Reactome)
Pathway description
Energy dependent regulation of mTOR by LKB1-AMPK
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000550 STRADA / Q5ZK47 / STE20-related kinase adapter protein alpha / Q7RTN6* / Q3UUJ4* / STE20-related kinase adaptor alpha*  / complex / reaction
 ENSGALG00000040008 STK11 / Q0GGW5 / Serine/threonine-protein kinase STK11 / Q9WTK7* / Q15831* / serine/threonine kinase 11*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr