ENSGALG00000027372


Gallus gallus

Features
Gene ID: ENSGALG00000027372
  
Biological name :PIP5K1A
  
Synonyms : phosphatidylinositol 4-phosphate 5-kinase type-1 alpha / PIP5K1A
  
Possible biological names infered from orthology : P70182 / Q99755
  
Species: Gallus gallus
  
Chr. number: 25
Strand: 1
Band:
Gene start: 2676126
Gene end: 2692345
  
Corresponding Affymetrix probe sets: GgaAffx.537.1.S1_s_at (Chicken Array)   GgaAffx.537.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001174
NCBI entrez gene - 429983     See in Manteia.
RefSeq - NM_001142440
RefSeq Peptide - NP_001135912
swissprot - H9KYX1
Ensembl - ENSGALG00000027372
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pip5k1aaENSDARG00000100396Danio rerio
 pip5k1abENSDARG00000024642Danio rerio
 Q99755ENSG00000143398Homo sapiens
 P70182ENSMUSG00000028126Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIP5K1C / Gallus gallus phosphatidylinositol-4-phosphate 5-kinase, type I, gamma (PIP5K1C), mRNA. / O60331* / O70161* / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma*ENSGALG0000000078457
PIP5K1B / phosphatidylinositol 4-phosphate 5-kinase type-1 beta / O14986* / P70181*ENSGALG0000001510749
PIP4K2B / phosphatidylinositol-5-phosphate 4-kinase type 2 beta / P78356* / Q80XI4*ENSGALG0000000161021
PIP4K2A / phosphatidylinositol 5-phosphate 4-kinase type-2 alpha / O70172* / P48426*ENSGALG0000000787720


Protein motifs (from Interpro)
Interpro ID Name
 IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
 IPR023610  Phosphatidylinositol-4-phosphate 5-kinase
 IPR027483  Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
 IPR027484  Phosphatidylinositol-4-phosphate 5-kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006661 phosphatidylinositol biosynthetic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0010761 fibroblast migration IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0048041 focal adhesion assembly IEA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0090630 activation of GTPase activity IEA
 biological_processGO:0097178 ruffle assembly IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016307 phosphatidylinositol phosphate kinase activity IEA
 molecular_functionGO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019900 kinase binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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