ENSGALG00000027534


Gallus gallus
processGM2Aactivitygangliosideactivatorcatabolicmd--relatedlipid-recognitiondomaingmlearningmemoryoligosaccharidelipidstorageregulationcatalyticnervousneuromuscularcontrollingbalancemitochondrionbeta-n-acetylhexosaminidaseenzymeglycosphingolipidmetabolismneutrophildegranulation

Features
Gene ID: ENSGALG00000027534
  
Biological name :GM2A
  
Synonyms : GM2A / GM2 ganglioside activator
  
Possible biological names infered from orthology : Ganglioside GM2 activator / P17900 / Q60648
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 13010726
Gene end: 13018170
  
Corresponding Affymetrix probe sets: Gga.1179.1.S1_s_at (Chicken Array)   Gga.15844.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042432
swissprot - Q5ZK02
Ensembl - ENSGALG00000027534
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gm2aENSDARG00000088439Danio rerio
 LO018208.1ENSDARG00000107431Danio rerio
 GM2AENSG00000196743Homo sapiens
 Gm2aENSMUSG00000000594Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003172  MD-2-related lipid-recognition domain
 IPR028996  Ganglioside GM2 activator


Gene Ontology (GO)
nitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processsystem processmacromolecule localizationregulation of biological qualityregulation of molecular functionnitrogen compounitrogen compound metabolic processcatabolic procecatabolic processcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processsystem processsystem processmacromolecule lmacromolecule localizationregulation of bregulation of biological qualityregulation of mregulation of molecular function
hydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityenzyme regulator activityhydrolase activityhydrolase activityenzyme regulator activityenzyme regulator activity
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006689 ganglioside catabolic process IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0009313 oligosaccharide catabolic process IEA
 biological_processGO:0019915 lipid storage IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0050877 nervous system process IEA
 biological_processGO:0050885 neuromuscular process controlling balance IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0004563 beta-N-acetylhexosaminidase activity IEA
 molecular_functionGO:0008047 enzyme activator activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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