ENSGALG00000027592


Gallus gallus

Features
Gene ID: ENSGALG00000027592
  
Biological name :ERN2
  
Synonyms : ERN2 / serine/threonine-protein kinase/endoribonuclease IRE2 precursor
  
Possible biological names infered from orthology : endoplasmic reticulum to nucleus signaling 2 / Q76MJ5 / Q9Z2E3 / Serine/threonine-protein kinase/endoribonuclease IRE2 Serine/threonine-protein kinase Endoribonuclease
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 6942340
Gene end: 6951189
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000040818
NCBI entrez gene - 771230     See in Manteia.
RefSeq - XM_015294257
RefSeq - NM_001285501
RefSeq - XM_015294255
RefSeq - XM_015294256
RefSeq Peptide - NP_001272430
swissprot - R4GFM3
Ensembl - ENSGALG00000027592
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ern2ENSDARG00000058475Danio rerio
 ERN2ENSG00000134398Homo sapiens
 Ern2ENSMUSG00000030866Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERN1 / endoplasmic reticulum to nucleus signaling 1 / O75460* / Q9EQY0* / Serine/threonine-protein kinase/endoribonuclease IRE1 Serine/threonine-protein kinase Endoribonuclease*ENSGALG0000000347656


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR010513  KEN domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR018391  Pyrrolo-quinoline quinone beta-propeller repeat
 IPR018997  PUB domain
 IPR033523  Serine/threonine-protein kinase/endoribonuclease IRE2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0016075 rRNA catabolic process IEA
 biological_processGO:0030263 apoptotic chromosome condensation IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 cellular_componentGO:1990604 IRE1-TRAF2-ASK1 complex IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004540 ribonuclease activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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