ENSGALG00000028928


Gallus gallus

Features
Gene ID: ENSGALG00000028928
  
Biological name :LCAT
  
Synonyms : LCAT / lecithin-cholesterol acyltransferase
  
Possible biological names infered from orthology : P04180 / P16301 / Phosphatidylcholine-sterol acyltransferase
  
Species: Gallus gallus
  
Chr. number: 11
Strand: -1
Band:
Gene start: 1094450
Gene end: 1100820
  
Corresponding Affymetrix probe sets: Gga.3257.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043323
NCBI entrez gene - 396136     See in Manteia.
RefSeq - NM_001293094
RefSeq Peptide - NP_001280023
swissprot - R4GM71
Ensembl - ENSGALG00000028928
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lcatENSDARG00000099424Danio rerio
 LCATENSG00000213398Homo sapiens
 LcatENSMUSG00000035237Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLA2G15 / phospholipase A2 group XV / Q8NCC3* / Q8VEB4* / Mus musculus phospholipase A2, group XV (Pla2g15), transcript variant 2, mRNA.*ENSGALG0000004178729


Protein motifs (from Interpro)
Interpro ID Name
 IPR003386  Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0006656 phosphatidylcholine biosynthetic process IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0030301 cholesterol transport IEA
 biological_processGO:0034372 very-low-density lipoprotein particle remodeling IEA
 biological_processGO:0034375 high-density lipoprotein particle remodeling IEA
 biological_processGO:0034435 cholesterol esterification IEA
 biological_processGO:0042158 lipoprotein biosynthetic process IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0043691 reverse cholesterol transport IEA
 biological_processGO:0046470 phosphatidylcholine metabolic process IEA
 biological_processGO:0090107 regulation of high-density lipoprotein particle assembly IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0034364 high-density lipoprotein particle IEA
 molecular_functionGO:0004607 phosphatidylcholine-sterol O-acyltransferase activity IEA
 molecular_functionGO:0008374 O-acyltransferase activity IEA
 molecular_functionGO:0034186 apolipoprotein A-I binding IEA


Pathways (from Reactome)
Pathway description
HDL remodeling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007114 APOA1 / P08250 / Apolipoprotein A-I Proapolipoprotein A-I / P02647* / Q00623* / apolipoprotein A1* / Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I*  / complex / reaction






 

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