ENSGALG00000030068


Gallus gallus
synapticRAB3Avesicleregulationneurotransmitterreleasebindingcyclesmallgtpaseproteindevelopmentexocytosispresynapticactivezonegtpsuperfamilygtp-bindingdomainp-loopcontainingnucleosidetriphosphatehydrolaserespiratoryprocessmitochondrionorganizationneuromusculartransmission

Features
Gene ID: ENSGALG00000030068
  
Biological name :RAB3A
  
Synonyms : RAB3A / RAB3A, member RAS oncogene family
  
Possible biological names infered from orthology : P20336 / P63011
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 4007204
Gene end: 4009764
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000049090
Ensembl peptide - ENSGALP00000052636
NCBI entrez gene - 107055371     See in Manteia.
RefSeq - XM_015300160
swissprot - A0A1D5P8P1
swissprot - A0A1D5PIK3
Ensembl - ENSGALG00000030068
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab3aaENSDARG00000056347Danio rerio
 rab3abENSDARG00000043835Danio rerio
 RAB3AENSG00000105649Homo sapiens
 Rab3aENSMUSG00000031840Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB3C / RAB3C, member RAS oncogene family / P62823* / Q96E17*ENSGALG0000001472666
RAB3B / RAB3B, member RAS oncogene family / P20337* / Q9CZT8*ENSGALG0000001056751
RAB8A / Q5F470 / Ras-related protein Rab-8A / P61006* / P55258* / RAB8A, member RAS oncogene family*ENSGALG0000002885137
RAB8B / RAB8B, member RAS oncogene family / P61028* / Q92930*ENSGALG0000000348735
RAB10 / ras-related protein Rab-10 / P61026* / P61027* / RAB10, member RAS oncogene family*ENSGALG0000001653534
RAB12 / RAB12, member RAS oncogene family / P35283* / Q6IQ22* / Ras-related protein Rab-12 *ENSGALG0000003360833
RAB27A / RAB27A, member RAS oncogene family / P51159* / Q9ERI2*ENSGALG0000000443531
ENSGALG0000001518328
RAB44 / RAB44, member RAS oncogene family / Q8CB87* / Ras-related protein Rab-44 *ENSGALG0000000054426
RASEF / RAS and EF-hand domain containing / Q5RI75* / Q8IZ41* / Ras and EF-hand domain-containing protein homolog *ENSGALG0000001257625
ENSGALG0000004648823


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
system processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem processrespiratory gaseous exchangecellular component organizationcell communicationanatomical structure developmentcellular developmental processestablishment of localizationregulation of biological qualitycellular localizationdevelopmental maturationresponse to abiotic stimulussystem procesystem processrespiratory respiratory gaseous exchangecellular comcellular component organizationcell communicell communicationanatomical sanatomical structure developmentcellular devcellular developmental processestablishmenestablishment of localizationregulation oregulation of biological qualitycellular loccellular localizationdevelopmentadevelopmental maturationresponse to response to abiotic stimulus
hydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindinghydrolase activityhydrolase activityion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingprotein bindingprotein binding
cellorganellesynapsecellorganellesynapsecellorganellesynapsecellorganellesynapsecellorganellesynapsecellorganellesynapsecellorganellesynapsecellorganellesynapsecellorganellesynapsecellorganellesynapsecellcellorganelleorganellesynapsesynapse
TypeGO IDTermEv.Code
 biological_processGO:0003016 respiratory system process IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0007274 neuromuscular synaptic transmission IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0016079 synaptic vesicle exocytosis IEA
 biological_processGO:0016188 synaptic vesicle maturation IEA
 biological_processGO:0017157 regulation of exocytosis IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0031630 regulation of synaptic vesicle fusion to presynaptic active zone membrane IEA
 biological_processGO:0048172 regulation of short-term neuronal synaptic plasticity IEA
 biological_processGO:0048790 maintenance of presynaptic active zone structure IEA
 biological_processGO:0050975 sensory perception of touch IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0061670 evoked neurotransmitter secretion IEA
 biological_processGO:1903307 positive regulation of regulated secretory pathway IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0043195 terminal bouton IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding IEA
 molecular_functionGO:0031489 myosin V binding IEA


Pathways (from Reactome)
Pathway description
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Neutrophil degranulation
RAB GEFs exchange GTP for GDP on RABs
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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