ENSGALG00000030396


Gallus gallus

Features
Gene ID: ENSGALG00000030396
  
Biological name :HMGA1
  
Synonyms : high mobility group AT-hook 1 / HMGA1
  
Possible biological names infered from orthology : High mobility group protein HMG-I/HMG-Y / Hmga1b / P17095 / P17096
  
Species: Gallus gallus
  
Chr. number: 26
Strand: -1
Band:
Gene start: 4415934
Gene end: 4417701
  
Corresponding Affymetrix probe sets: Gga.9262.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051697
NCBI entrez gene - 378795     See in Manteia.
RefSeq - NM_204369
RefSeq Peptide - NP_989700
swissprot - Q6W8X3
Ensembl - ENSGALG00000030396
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmga1aENSDARG00000028335Danio rerio
 hmga1bENSDARG00000070951Danio rerio
 HMGA1ENSG00000137309Homo sapiens
 Hmga1ENSMUSG00000046711Mus musculus
 Hmga1bENSMUSG00000078249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000116  High mobility group protein HMGA
 IPR000637  HMG-I/HMG-Y, DNA-binding, conserved site
 IPR017956  AT hook, DNA-binding motif
 IPR031079  High mobility group protein HMGA1, mammal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0035986 senescence-associated heterochromatin focus assembly IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0090402 oncogene-induced cell senescence IEA
 biological_processGO:2000774 positive regulation of cellular senescence IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0035985 senescence-associated heterochromatin focus IEA
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003680 AT DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IEA
 molecular_functionGO:0042974 retinoic acid receptor binding IEA
 molecular_functionGO:0042975 peroxisome proliferator activated receptor binding IEA
 molecular_functionGO:0046965 retinoid X receptor binding IEA


Pathways (from Reactome)
Pathway description
Formation of Senescence-Associated Heterochromatin Foci (SAHF)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006363 CABIN1 / calcineurin binding protein 1 / Q9Y6J0*  / complex / reaction
 ENSGALG00000009875 HMGA2 / high mobility group AT-hook 2 / P52926* / P52927*  / complex / reaction
 ENSGALG00000014887 ASF1A / Q3C1E9 / Histone chaperone ASF1 / Q9CQE6* / Q9Y294* / Histone chaperone ASF1A * / anti-silencing function 1A histone chaperone*  / complex / reaction
 ENSGALG00000031416 UBN1 / ubinuclein 1 / Q4G0F8* / Q9NPG3*  / complex / reaction
 ENSGALG00000033598 HIRA / histone cell cycle regulator / P54198* / Q61666* / Protein HIRA *  / complex / reaction
 ENSGALG00000044240 H1F0 / P02259 / Histone H5 / P07305* / P10922* / H1 histone family member 0* / Histone H1.0 Histone H1.0, N-terminally processed*  / reaction






 

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