ENSGALG00000031182


Gallus gallus

Features
Gene ID: ENSGALG00000031182
  
Biological name :FANCM
  
Synonyms : A0A1D5PRR9 / FANCM / Fanconi anemia group M protein
  
Possible biological names infered from orthology : Fanconi anemia complementation group M / Fanconi anemia group M protein homolog / Q8BGE5 / Q8IYD8
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 58868218
Gene end: 58927474
  
Corresponding Affymetrix probe sets: Gga.6023.1.S1_at (Chicken Array)   GgaAffx.23918.1.S1_at (Chicken Array)   GgaAffx.23918.1.S1_s_at (Chicken Array)   GgaAffx.7905.1.S1_at (Chicken Array)   GgaAffx.7906.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055597
NCBI entrez gene - 100857997     See in Manteia.
RefSeq - XM_015276780
RefSeq - XM_015276781
swissprot - A0A1D5PRR9
Ensembl - ENSGALG00000031182
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079748.1ENSDARG00000112136Danio rerio
 fancmENSDARG00000103933Danio rerio
 FANCMENSG00000187790Homo sapiens
 FancmENSMUSG00000055884Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DICER1 / endoribonuclease Dicer / Q9UPY3* / dicer 1, ribonuclease III*ENSGALG0000001099910
DHX58 / Gallus gallus DExH-box helicase 58 (DHX58), mRNA. / Q96C10* / Q99J87* / DExH-box helicase 58* / Probable ATP-dependent RNA helicase DHX58 *ENSGALG000000238217
IFIH1 / interferon-induced helicase C domain-containing protein 1 / Q8R5F7* / Q9BYX4* / interferon induced with helicase C domain 1*ENSGALG000000411927


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR006166  ERCC4 domain
 IPR006935  Helicase/UvrB, N-terminal
 IPR010994  RuvA domain 2-like
 IPR011335  Restriction endonuclease type II-like
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031879  Fanconi anemia group M protein, MHF binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0031297 replication fork processing IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0043240 Fanconi anaemia nuclear complex IEA
 cellular_componentGO:0071821 FANCM-MHF complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000024481 CENPS / E1BSW7 / Centromere protein S / Q8N2Z9* / Q9D084* / CENPS-CORT* / CENPS-CORT readthrough*  / complex
 ENSGALG00000034534 FAAP24 / Fanconi anemia core complex associated protein 24 / Q8BHL6* / Q9BTP7*  / complex / reaction
 ENSGALG00000043607 CENPX / A8MT69* / Q8C4X1* / centromere protein X* / Mus musculus centromere protein X (Cenpx), transcript variant 3, mRNA.*  / complex






 

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