ENSGALG00000031511


Gallus gallus

Features
Gene ID: ENSGALG00000031511
  
Biological name :HIP1R
  
Synonyms : HIP1R / huntingtin-interacting protein 1-related protein
  
Possible biological names infered from orthology : huntingtin interacting protein 1 related / O75146 / Q9JKY5
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 5289267
Gene end: 5303607
  
Corresponding Affymetrix probe sets: Gga.5742.1.S1_s_at (Chicken Array)   GgaAffx.12396.1.S1_at (Chicken Array)   GgaAffx.2363.1.S1_s_at (Chicken Array)   GgaAffx.2372.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050552
NCBI entrez gene - 416836     See in Manteia.
RefSeq - NM_001030657
RefSeq - XM_015275277
RefSeq - XM_015275278
RefSeq Peptide - NP_001025828
swissprot - A0A1D5PCR1
Ensembl - ENSGALG00000031511
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hip1raENSDARG00000060627Danio rerio
 hip1rbENSDARG00000102458Danio rerio
 HIP1RENSG00000130787Homo sapiens
 Hip1rENSMUSG00000000915Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HIP1 / huntingtin interacting protein 1 / O00291* / Q8VD75*ENSGALG0000004090847
TLN1 / talin-1 / P26039* / Q9Y490*ENSGALG0000000254823
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000036289
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000380782
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000461552
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000466182
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000298161


Protein motifs (from Interpro)
Interpro ID Name
 IPR002558  I/LWEQ domain
 IPR008942  ENTH/VHS
 IPR011417  AP180 N-terminal homology (ANTH) domain
 IPR013809  ENTH domain
 IPR030224  Sla2 family
 IPR030555  Huntingtin-interacting protein 1-related protein
 IPR032422  Huntingtin-interacting protein 1, clathrin-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0030100 regulation of endocytosis IEA
 biological_processGO:0030837 negative regulation of actin filament polymerization IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0048268 clathrin coat assembly IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0055123 digestive system development IEA
 biological_processGO:0060453 regulation of gastric acid secretion IEA
 biological_processGO:0061024 membrane organization IEA
 biological_processGO:0072583 clathrin-dependent endocytosis IEA
 biological_processGO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IEA
 biological_processGO:1905445 positive regulation of clathrin coat assembly IEA
 biological_processGO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0030276 clathrin binding IEA
 molecular_functionGO:0032051 clathrin light chain binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0035615 clathrin adaptor activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051015 actin filament binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr