ENSGALG00000032191


Gallus gallus

Features
Gene ID: ENSGALG00000032191
  
Biological name :WNK4
  
Synonyms : WNK4 / WNK lysine deficient protein kinase 4
  
Possible biological names infered from orthology : Q80UE6 / Q96J92
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 5462100
Gene end: 5472837
  
Corresponding Affymetrix probe sets: Gga.1544.1.S1_at (Chicken Array)   GgaAffx.1907.1.S1_s_at (Chicken Array)   GgaAffx.25708.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057050
NCBI entrez gene - 777580     See in Manteia.
RefSeq - XM_015299609
swissprot - A0A1D5PVS4
Ensembl - ENSGALG00000032191
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnk4bENSDARG00000088967Danio rerio
 WNK4ENSG00000126562Homo sapiens
 Wnk4ENSMUSG00000035112Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNK1 / WNK lysine deficient protein kinase 1 / P83741* / Q9H4A3*ENSGALG0000001299239
WNK2 / WNK lysine deficient protein kinase 2 / Q9Y3S1*ENSGALG0000003885037
NRBP1 / nuclear receptor-binding protein / Q99J45* / Q9UHY1* / nuclear receptor binding protein 1* / Mus musculus nuclear receptor binding protein 1 (Nrbp1), transcript variant 1, mRNA.*ENSGALG0000001651211
NRBP2 / nuclear receptor binding protein 2 / Q91V36* / Q9NSY0* / Mus musculus nuclear receptor binding protein 2 (Nrbp2), transcript variant 1, mRNA.*ENSGALG000000297607


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR024678  Serine/threonine-protein kinase OSR1/WNK, CCT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0050794 regulation of cellular process IEA
 biological_processGO:0050801 ion homeostasis IEA
 biological_processGO:0070294 renal sodium ion absorption IEA
 biological_processGO:0072156 distal tubule morphogenesis IEA
 biological_processGO:0090188 negative regulation of pancreatic juice secretion IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019869 chloride channel inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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