ENSGALG00000033162


Gallus gallus

Features
Gene ID: ENSGALG00000033162
  
Biological name :PSMD3
  
Synonyms : 26S proteasome non-ATPase regulatory subunit 3 / PSMD3
  
Possible biological names infered from orthology : O43242 / P14685 / proteasome 26S subunit, non-ATPase 3
  
Species: Gallus gallus
  
Chr. number: 27
Strand: 1
Band:
Gene start: 4729921
Gene end: 4735633
  
Corresponding Affymetrix probe sets: Gga.4645.3.S1_s_at (Chicken Array)   GgaAffx.13196.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045115
Ensembl peptide - ENSGALP00000064485
Ensembl peptide - ENSGALP00000062930
Ensembl peptide - ENSGALP00000059463
Ensembl peptide - ENSGALP00000049406
NCBI entrez gene - 426133     See in Manteia.
RefSeq - NM_001031362
RefSeq Peptide - NP_001026533
swissprot - A0A1L1RL24
swissprot - A0A1L1S033
swissprot - A0A1D5NXL7
swissprot - A0A1D5P9K2
swissprot - A0A1L1RVR6
Ensembl - ENSGALG00000033162
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 psmd3ENSDARG00000018124Danio rerio
 PSMD3ENSG00000108344Homo sapiens
 Psmd3ENSMUSG00000017221Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013586  26S proteasome regulatory subunit, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042176 regulation of protein catabolic process IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005838 proteasome regulatory particle IEA
 cellular_componentGO:0022624 proteasome accessory complex IEA
 molecular_functionGO:0030234 enzyme regulator activity IEA


Pathways (from Reactome)
Pathway description
GLI3 is processed to GLI3R by the proteasome
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Regulation of RUNX3 expression and activity
MAPK6/MAPK4 signaling
TNFR2 non-canonical NF-kB pathway
Neddylation
SCF-beta-TrCP mediated degradation of Emi1
Autodegradation of Cdh1 by Cdh1:APC/C
Regulation of PTEN stability and activity
Regulation of RUNX2 expression and activity
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Autodegradation of the E3 ubiquitin ligase COP1
FCERI mediated NF-kB activation
Separation of Sister Chromatids
Degradation of beta-catenin by the destruction complex
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Cross-presentation of soluble exogenous antigens (endosomes)
AUF1 (hnRNP D0) binds and destabilizes mRNA
ABC-family proteins mediated transport
Activation of NF-kappaB in B cells
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
APC/C:Cdc20 mediated degradation of Securin
Antigen processing: Ubiquitination & Proteasome degradation
Asymmetric localization of PCP proteins
CLEC7A (Dectin-1) signaling
CDT1 association with the CDC6:ORC:origin complex
CDK-mediated phosphorylation and removal of Cdc6
Degradation of GLI1 by the proteasome
Degradation of DVL
Degradation of AXIN
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Downstream TCR signaling
Hedgehog on state
Hedgehog ligand biogenesis
Interleukin-1 signaling
Orc1 removal from chromatin
Neutrophil degranulation
Regulation of RAS by GAPs
Regulation of ornithine decarboxylase (ODC)
SCF(Skp2)-mediated degradation of p27/p21
Ub-specific processing proteases
UCH proteinases
Ubiquitin-dependent degradation of Cyclin D1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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