ENSGALG00000033278


Gallus gallus

Features
Gene ID: ENSGALG00000033278
  
Biological name :NLRC3
  
Synonyms : NLRC3 / NLR family CARD domain containing 3
  
Possible biological names infered from orthology : Protein NLRC3 / Q5DU56 / Q7RTR2
  
Species: Gallus gallus
  
Chr. number: 14
Strand: 1
Band:
Gene start: 12811777
Gene end: 12820369
  
Corresponding Affymetrix probe sets: GgaAffx.4901.1.S1_s_at (Chicken Array)   GgaAffx.4901.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044725
Ensembl peptide - ENSGALP00000047886
NCBI entrez gene - 416673     See in Manteia.
RefSeq - XM_015294675
RefSeq - XM_015294676
RefSeq - XM_015294677
swissprot - A0A1D5P5B9
swissprot - A0A1D5NWI5
Ensembl - ENSGALG00000033278
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nlrc3ENSDARG00000103146Danio rerio
 NLRC3ENSG00000167984Homo sapiens
 Nlrc3ENSMUSG00000049871Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLRC5 / Gallus gallus NLR family CARD domain containing 5 (NLRC5), mRNA. / C3VPR6* / Q86WI3* / Protein NLRC5 * / NLR family CARD domain containing 5*ENSGALG0000000125619
NOD1 / Gallus gallus nucleotide binding oligomerization domain containing 1 (NOD1), mRNA. / Q8BHB0* / Q9Y239* / nucleotide binding oligomerization domain containing 1* / Nucleotide-binding ...ENSGALG0000003680719
NLRX1 / NLR family member X1 / Q3TL44* / Q86UT6*ENSGALG0000004405315
CIITA / class II major histocompatibility complex transactivator / P33076* / P79621* / MHC class II transactivator *ENSGALG0000000717114


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR001611  Leucine-rich repeat
 IPR007111  NACHT nucleoside triphosphatase
 IPR011029  Death-like domain superfamily
 IPR029495  NACHT-associated domain
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0032715 negative regulation of interleukin-6 production IEA
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IEA
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:1900226 negative regulation of NLRP3 inflammasome complex assembly IEA
 biological_processGO:1901223 negative regulation of NIK/NF-kappaB signaling IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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