ENSGALG00000035462


Gallus gallus

Features
Gene ID: ENSGALG00000035462
  
Biological name :IREB2
  
Synonyms : IREB2 / iron-responsive element-binding protein 2
  
Possible biological names infered from orthology : P48200 / Q811J3
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 3599365
Gene end: 3621150
  
Corresponding Affymetrix probe sets: Gga.1321.1.S1_s_at (Chicken Array)   Gga.1321.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054976
Ensembl peptide - ENSGALP00000060764
NCBI entrez gene - 427490     See in Manteia.
RefSeq - NM_001031454
RefSeq Peptide - NP_001026625
swissprot - A0A1L1RPQ4
swissprot - A0A1D5PQ17
Ensembl - ENSGALG00000035462
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ireb2ENSDARG00000021466Danio rerio
 IREB2ENSG00000136381Homo sapiens
 Ireb2ENSMUSG00000032293Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACO1 / cytoplasmic aconitate hydratase / P21399* / P28271* / aconitase 1*ENSGALG0000000216257


Protein motifs (from Interpro)
Interpro ID Name
 IPR000573  Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
 IPR001030  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
 IPR006249  Aconitase/Iron-responsive element-binding protein 2
 IPR015928  Aconitase/3-isopropylmalate dehydratase, swivel
 IPR015931  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
 IPR015932  Aconitase, domain 2
 IPR018136  Aconitase family, 4Fe-4S cluster binding site
 IPR029755  Iron regulatory protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006782 protoporphyrinogen IX biosynthetic process IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0030316 osteoclast differentiation IEA
 biological_processGO:0034101 erythrocyte homeostasis IEA
 biological_processGO:0050892 intestinal absorption IEA
 biological_processGO:0055072 iron ion homeostasis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0030350 iron-responsive element binding IEA
 molecular_functionGO:0030371 translation repressor activity IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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