ENSGALG00000035935


Gallus gallus
domainUNC13Cbindinghomologyproteinmammalianuncoordinatedsynapticintracellularionckinasec-likephorbolesterdiacylglycerol-bindingcalcium-dependentsecretionactivatormuncsubgroupunc-chemicaltransmissionregulationplasticitysignaltransductioncalyxheldpresynapse

Features
Gene ID: ENSGALG00000035935
  
Biological name :UNC13C
  
Synonyms : UNC13C / unc-13 homolog C
  
Possible biological names infered from orthology : Q8K0T7 / Q8NB66 / unc-13 homolog C (C. elegans)
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 8129598
Gene end: 8287922
  
Corresponding Affymetrix probe sets: Gga.10843.1.S1_s_at (Chicken Array)   GgaAffx.2796.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043800
Ensembl peptide - ENSGALP00000052258
Ensembl peptide - ENSGALP00000045380
NCBI entrez gene - 415413     See in Manteia.
RefSeq - XM_015291889
RefSeq - XM_015291890
RefSeq - XM_015291891
RefSeq - XM_413798
swissprot - A0A1D5NYC3
swissprot - A0A1D5NTZ3
swissprot - A0A1D5PHH9
Ensembl - ENSGALG00000035935
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01117752.1ENSDARG00000115552Danio rerio
 Q8NB66ENSG00000137766Homo sapiens
 Q8K0T7ENSMUSG00000062151Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UNC13B / unc-13 homolog B / O14795* / Q9Z1N9* / unc-13 homolog B (C. elegans)*ENSGALG0000000216565
ENSGALG0000004137165


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR010439  Calcium-dependent secretion activator domain
 IPR014770  Munc13 homology 1
 IPR014772  Mammalian uncoordinated homology 13, domain 2
 IPR019558  Mammalian uncoordinated homology 13, subgroup, domain 2
 IPR027080  Protein Unc-13


Gene Ontology (GO)
cell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationregulation of biological qualitycellular response to stimuluscell communicationcell communicationregulation of biological qualityregulation of biological qualitycellular response to stimuluscellular response to stimulus
ion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindinglipid bindingion bindingion bindinglipid bindinglipid binding
cellsynapsecellsynapsecellsynapsecellsynapsecellsynapsecellsynapsecellsynapsecellsynapsecellsynapsecellsynapsecellcellsynapsesynapse
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0031914 negative regulation of synaptic plasticity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0044305 calyx of Held IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0019992 diacylglycerol binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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