ENSGALG00000036456


Gallus gallus

Features
Gene ID: ENSGALG00000036456
  
Biological name :TRIB1
  
Synonyms : TRIB1 / tribbles pseudokinase 1
  
Possible biological names infered from orthology : Q8K4K4 / Q96RU8 / Tribbles homolog 1
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 138969888
Gene end: 138972814
  
Corresponding Affymetrix probe sets: GgaAffx.10443.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051569
NCBI entrez gene - 428386     See in Manteia.
RefSeq - XM_015283145
swissprot - A0A1D5PFK2
Ensembl - ENSGALG00000036456
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trib1ENSDARG00000110963Danio rerio
 TRIB1ENSG00000173334Homo sapiens
 Trib1ENSMUSG00000032501Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRIB2 / tribbles homolog 2 / Q8K4K3* / Q92519* / tribbles pseudokinase 2*ENSGALG0000001645752
NUAK1 / NUAK family kinase 1 / O60285* / Q641K5* / NUAK family SNF1-like kinase 1 *ENSGALG0000001266225
STK40 / serine/threonine-protein kinase 40 / Q7TNL3* / Q8N2I9* / serine/threonine kinase 40*ENSGALG0000003292524
NUAK2 / NUAK family kinase 2 / Q8BZN4* / Q9H093* / NUAK family SNF1-like kinase 2 *ENSGALG0000003661624
PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2 / P54646* / Q8BRK8* / protein kinase, AMP-activated, alpha 2 catalytic subunit*ENSGALG0000001082621
PRKAA1 / protein kinase AMP-activated catalytic subunit alpha 1 / Q13131* / Q5EG47* / protein kinase, AMP-activated, alpha 1 catalytic subunit*ENSGALG0000001483220


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR024104  Pseudokinase tribbles family/serine-threonine-protein kinase 40
 IPR024105  Tribbles homologue 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0007254 JNK cascade IEA
 biological_processGO:0014912 negative regulation of smooth muscle cell migration IEA
 biological_processGO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0043405 regulation of MAP kinase activity IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045645 positive regulation of eosinophil differentiation IEA
 biological_processGO:0045651 positive regulation of macrophage differentiation IEA
 biological_processGO:0045659 negative regulation of neutrophil differentiation IEA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0055106 ubiquitin-protein transferase regulator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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