ENSGALG00000037082


Gallus gallus

Features
Gene ID: ENSGALG00000037082
  
Biological name :ASCL1
  
Synonyms : achaete-scute homolog 1 / ASCL1
  
Possible biological names infered from orthology : achaete-scute family bHLH transcription factor 1 / P50553 / Q02067
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 55116728
Gene end: 55118741
  
Corresponding Affymetrix probe sets: Gga.488.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047577
NCBI entrez gene - 386573     See in Manteia.
RefSeq - NM_204412
RefSeq Peptide - NP_989743
swissprot - A0A1D5P4G9
Ensembl - ENSGALG00000037082
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ascl1aENSDARG00000038386Danio rerio
 ASCL1ENSG00000139352Homo sapiens
 Ascl1ENSMUSG00000020052Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASCL4 / achaete-scute family bHLH transcription factor 4 / Q6XD76*ENSGALG0000001930421
ASCL3 / achaete-scute family bHLH transcription factor 3 / Q9JJR7* / Q9NQ33* / Achaete-scute homolog 3 *ENSGALG0000003672521


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR015660  Achaete-scute transcription factor-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0003358 noradrenergic neuron development IEA
 biological_processGO:0003359 noradrenergic neuron fate commitment IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IEA
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007400 neuroblast fate determination IEA
 biological_processGO:0007405 neuroblast proliferation IEA
 biological_processGO:0008593 regulation of Notch signaling pathway IEA
 biological_processGO:0010001 glial cell differentiation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0021527 spinal cord association neuron differentiation IEA
 biological_processGO:0021529 spinal cord oligodendrocyte cell differentiation IEA
 biological_processGO:0021530 spinal cord oligodendrocyte cell fate specification IEA
 biological_processGO:0021750 vestibular nucleus development IEA
 biological_processGO:0021779 oligodendrocyte cell fate commitment IEA
 biological_processGO:0021892 cerebral cortex GABAergic interneuron differentiation IEA
 biological_processGO:0021902 commitment of neuronal cell to specific neuron type in forebrain IEA
 biological_processGO:0021954 central nervous system neuron development IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0022008 neurogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030856 regulation of epithelial cell differentiation IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048663 neuron fate commitment IEA
 biological_processGO:0048665 neuron fate specification IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0048699 generation of neurons IEA
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:0050883 musculoskeletal movement, spinal reflex action IEA
 biological_processGO:0060163 subpallium neuron fate commitment IEA
 biological_processGO:0060165 regulation of timing of subpallium neuron differentiation IEA
 biological_processGO:0060166 olfactory pit development IEA
 biological_processGO:0060579 ventral spinal cord interneuron fate commitment IEA
 biological_processGO:0061100 lung neuroendocrine cell differentiation IEA
 biological_processGO:0061102 stomach neuroendocrine cell differentiation IEA
 biological_processGO:0061103 carotid body glomus cell differentiation IEA
 biological_processGO:0061104 adrenal chromaffin cell differentiation IEA
 biological_processGO:0061549 sympathetic ganglion development IEA
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000989 transcription factor activity, transcription factor binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043425 bHLH transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0070888 E-box binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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