ENSGALG00000037781


Gallus gallus

Features
Gene ID: ENSGALG00000037781
  
Biological name :GSR
  
Synonyms : glutathione-disulfide reductase / GSR
  
Possible biological names infered from orthology : Glutathione reductase, mitochondrial / P00390 / P47791
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 34885417
Gene end: 34890567
  
Corresponding Affymetrix probe sets: Gga.18213.1.S1_at (Chicken Array)   Gga.8446.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047092
Ensembl peptide - ENSGALP00000061663
Ensembl peptide - ENSGALP00000061437
Ensembl peptide - ENSGALP00000060447
Ensembl peptide - ENSGALP00000059356
NCBI entrez gene - 771783     See in Manteia.
RefSeq - XM_015276627
swissprot - A0A1L1RS82
swissprot - A0A1L1RRK5
swissprot - A0A1L1RNU1
swissprot - A0A1L1RKR6
swissprot - A0A1D5P338
Ensembl - ENSGALG00000037781
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsrENSDARG00000019236Danio rerio
 GSRENSG00000104687Homo sapiens
 GsrENSMUSG00000031584Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TXNRD3 / thioredoxin reductase 3 / Q86VQ6*ENSGALG0000003936337
TXNRD2 / thioredoxin reductase 2, mitochondrial precursor / Q9NNW7* / thioredoxin reductase 2*ENSGALG0000000198836
TXNRD1 / Gallus gallus thioredoxin reductase 1 (TXNRD1), transcript variant 2, mRNA. / Q16881* / Q9JMH6* / thioredoxin reductase 1*ENSGALG0000003534535


Protein motifs (from Interpro)
Interpro ID Name
 IPR004099  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
 IPR006322  Glutathione reductase, eukaryote/bacterial
 IPR012999  Pyridine nucleotide-disulphide oxidoreductase, class I, active site
 IPR016156  FAD/NAD-linked reductase, dimerisation domain superfamily
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 molecular_functionGO:0004362 glutathione-disulfide reductase activity IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0050661 NADP binding IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species
Interconversion of nucleotide di- and triphosphates
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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