ENSGALG00000038848


Gallus gallus

Features
Gene ID: ENSGALG00000038848
  
Biological name :MSX2
  
Synonyms : Homeobox protein MSX-2 / MSX2 / P28362
  
Possible biological names infered from orthology : msh homeobox 2 / P35548 / Q03358
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 9797292
Gene end: 9802103
  
Corresponding Affymetrix probe sets: Gga.14494.1.S1_at (Chicken Array)   Gga.4977.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000059847
Ensembl peptide - ENSGALP00000046638
NCBI entrez gene - 395245     See in Manteia.
RefSeq - NM_204559
RefSeq Peptide - NP_989890
swissprot - P28362
swissprot - A0A1L1RM54
Ensembl - ENSGALG00000038848
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 msx2bENSDARG00000101023Danio rerio
 MSX2ENSG00000120149Homo sapiens
 Msx2ENSMUSG00000021469Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MSX1 / P50223 / Homeobox protein GHOX-7 / P13297* / P28360* / msh homeobox 1* / Homeobox protein MSX-1 *ENSGALG0000001501358
DLX6 / homeobox protein DLX-6 / P56179* / P70397* / distal-less homeobox 6*ENSGALG0000002319522
DLX2 / distal-less homeobox 2 / P40764* / Q07687* / Homeobox protein DLX-2 *ENSGALG0000003943622
DLX5 / P50577 / Homeobox protein DLX-5 / P56178* / P70396* / distal-less homeobox 5*ENSGALG0000000912921
DLX1 / homeobox protein DLX-1 / P56177* / Q64317* / distal-less homeobox 1*ENSGALG0000001843920
DLX3 / Gallus gallus distal-less homeobox 3 (DLX3), mRNA. / O60479* / Q64205* / distal-less homeobox 3* / Homeobox protein DLX-3 *ENSGALG0000004052920
DLX4 / distal-less homeobox 4 / P70436* / Q92988* / Homeobox protein DLX-4 *ENSGALG0000004502318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0002063 chondrocyte development IEA
 biological_processGO:0002076 osteoblast development IEA
 biological_processGO:0003148 outflow tract septum morphogenesis IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation IEA
 biological_processGO:0003416 endochondral bone growth IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0032792 negative regulation of CREB transcription factor activity IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0035313 wound healing, spreading of epidermal cells IEA
 biological_processGO:0035880 embryonic nail plate morphogenesis IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042476 odontogenesis IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045617 negative regulation of keratinocyte differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0051795 positive regulation of timing of catagen IEA
 biological_processGO:0060346 bone trabecula formation IEA
 biological_processGO:0060349 bone morphogenesis IEA
 biological_processGO:0060364 frontal suture morphogenesis IEA
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0061180 mammary gland epithelium development IEA
 biological_processGO:0061312 BMP signaling pathway involved in heart development IEA
 biological_processGO:0070166 enamel mineralization IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:0090427 activation of meiosis IEA
 biological_processGO:2000678 negative regulation of transcription regulatory region DNA binding IEA
 biological_processGO:2001055 positive regulation of mesenchymal cell apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000989 transcription factor activity, transcription factor binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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