ENSGALG00000038941


Gallus gallus

Features
Gene ID: ENSGALG00000038941
  
Biological name :BRK1
  
Synonyms : BRICK1, SCAR/WAVE actin nucleating complex subunit / BRK1
  
Possible biological names infered from orthology : Protein BRICK1 / Q8WUW1 / Q91VR8
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 2736852
Gene end: 2737239
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000053090
NCBI entrez gene - 107054369     See in Manteia.
RefSeq - XM_015292880
swissprot - A0A1D5PJU4
Ensembl - ENSGALG00000038941
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brk1ENSDARG00000041974Danio rerio
 BRK1ENSG00000254999Homo sapiens
 Brk1ENSMUSG00000033940Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR033378  Protein BRICK1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010592 positive regulation of lamellipodium assembly IEA
 biological_processGO:0016601 Rac protein signal transduction IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0048870 cell motility IEA
 biological_processGO:0070207 protein homotrimerization IEA
 biological_processGO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0031209 SCAR complex IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr