ENSGALG00000040573


Gallus gallus
flavinFMO3fmoactivitymembranebindingmonooxygenase-likefadnadp-bindingdomainoxidation-reductionprocessintegralcomponentnn-dimethylanilineoxidoreductaseadeninedinucleotidenadpoxidisesnucleophiles

Features
Gene ID: ENSGALG00000040573
  
Biological name :FMO3
  
Synonyms : flavin containing monooxygenase 3 / FMO3
  
Possible biological names infered from orthology : Dimethylaniline monooxygenase [N-oxide-forming] 3 / Fmo6 / P31513 / P97501
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 4824822
Gene end: 4831264
  
Corresponding Affymetrix probe sets: Gga.4564.1.S1_a_at (Chicken Array)   Gga.4564.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053108
NCBI entrez gene - 395267     See in Manteia.
RefSeq - NM_204579
RefSeq Peptide - NP_989910
swissprot - Q8QH01
Ensembl - ENSGALG00000040573
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fmo5ENSDARG00000016357Danio rerio
 si:dkey-239i20.2ENSDARG00000043518Danio rerio
 si:dkey-239i20.4ENSDARG00000043514Danio rerio
 FMO3ENSG00000007933Homo sapiens
 Fmo3ENSMUSG00000026691Mus musculus
 Fmo6ENSMUSG00000095576Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FMO4 / flavin containing monooxygenase 4 / P31512* / Q8VHG0* / Dimethylaniline monooxygenase [N-oxide-forming] 4 *ENSGALG0000004029253
FMO5* / P49326* / P97872* / flavin containing monooxygenase 5* / Mus musculus flavin containing monooxygenase 5 (Fmo5), transcript variant 4, mRNA.*ENSGALG0000000172352
FMO5* / P49326* / P97872* / flavin containing monooxygenase 5* / Mus musculus flavin containing monooxygenase 5 (Fmo5), transcript variant 4, mRNA.*ENSGALG0000000302251


Protein motifs (from Interpro)
Interpro ID Name
 IPR000960  Flavin monooxygenase FMO
 IPR002255  Flavin monooxygenase (FMO) 3
 IPR020946  Flavin monooxygenase-like
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
oxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction processoxidation-reduction process
oxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityion bindingorganic cyclic compound bindingheterocyclic compound bindingcofactor bindingsmall molecule bindingoxidoreductase activityoxidoreductase activityion bindingion bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingcofactor bindingcofactor bindingsmall molecule bindingsmall molecule binding
membranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IBA
 molecular_functionGO:0004499 N,N-dimethylaniline monooxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0050661 NADP binding IEA


Pathways (from Reactome)
Pathway description
FMO oxidises nucleophiles


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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