ENSGALG00000040724


Gallus gallus

Features
Gene ID: ENSGALG00000040724
  
Biological name :AKAP9
  
Synonyms : AKAP9 / A-kinase anchoring protein 9
  
Possible biological names infered from orthology : Q99996
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 22422267
Gene end: 22521442
  
Corresponding Affymetrix probe sets: Gga.9661.1.S1_at (Chicken Array)   GgaAffx.5870.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054390
NCBI entrez gene - 395695     See in Manteia.
RefSeq - NM_207179
RefSeq Peptide - NP_997062
swissprot - A0A1D5PNE9
Ensembl - ENSGALG00000040724
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akap9ENSDARG00000079610Danio rerio
 AKAP9ENSG00000127914Homo sapiens
 Akap9ENSMUSG00000040407Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCNT / pericentrin / O95613*ENSGALG0000000702118


Protein motifs (from Interpro)
Interpro ID Name
 IPR005539  ELK domain
 IPR019528  Pericentrin/AKAP-450 centrosomal targeting domain
 IPR028745  A-kinase anchor protein 9/Pericentrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007020 microtubule nucleation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0031116 positive regulation of microtubule polymerization IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0051661 maintenance of centrosome location IEA
 biological_processGO:0060306 regulation of membrane repolarization IEA
 biological_processGO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization IEA
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction IEA
 biological_processGO:1901018 positive regulation of potassium ion transmembrane transporter activity IEA
 biological_processGO:1903358 regulation of Golgi organization IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005801 cis-Golgi network IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0015459 potassium channel regulator activity IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IEA
 molecular_functionGO:0044325 ion channel binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Unblocking of NMDA receptor, glutamate binding and activation
CREB phosphorylation through the activation of CaMKII
Ras activation upon Ca2+ influx through NMDA receptor
Phase 3 - rapid repolarisation
Phase 2 - plateau phase
Anchoring of the basal body to the plasma membrane
RAF/MAP kinase cascade
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004083 GRIA1 / glutamate ionotropic receptor AMPA type subunit 1 / P23818* / P42261* / Glutamate receptor 1 *  / reaction
 ENSGALG00000038995 GRIA4 / glutamate receptor 4 isoform 1 precursor / P48058* / Q9Z2W8* / glutamate receptor, ionotropic, AMPA4 (alpha 4)* / glutamate ionotropic receptor AMPA type subunit 4*  / reaction
 ENSGALG00000030793 KCNE2 / potassium voltage-gated channel subfamily E regulatory subunit 2 / Q9Y6J6* / Mus musculus potassium voltage-gated channel, Isk-related subfamily, 2 (Kcne2), transcript variant 2, mRNA.*  / complex
 ENSGALG00000000314 NEFL / neurofilament light / P07196* / P08551* / Neurofilament light polypeptide *  / complex
 ENSGALG00000005621 CAMK2A / calcium/calmodulin-dependent protein kinase type II subunit alpha / P11798* / Q9UQM7* / calcium/calmodulin dependent protein kinase II alpha*  / complex / reaction
 ENSGALG00000007278 GRIN2A / glutamate ionotropic receptor NMDA type subunit 2A / P35436* / Q12879* / Glutamate receptor ionotropic, NMDA 2A *  / complex
 ENSGALG00000014463 ACTN2 / P20111 / Alpha-actinin-2 / P35609* / Q9JI91* / actinin alpha 2*  / complex
 ENSGALG00000010023 CALM2 / P62149 / Calmodulin / Calm3* / CALM1* / P0DP23* / P0DP26* / P0DP27* / P0DP28* / calmodulin 1*  / complex / reaction
 ENSGALG00000015598 RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2 / O14827* / ras-specific guanine nucleotide-releasing factor 2 *  / complex / reaction
 ENSGALG00000027415 GRIN2C / glutamate ionotropic receptor NMDA type subunit 2C / Q01098* / Q14957* / Glutamate receptor ionotropic, NMDA 2C *  / complex
 ENSGALG00000008898 GRIN1 / glutamate ionotropic receptor NMDA type subunit 1 / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 *  / complex
 ENSGALG00000029260 H-RAS / P08642 / GTPase HRas GTPase HRas, N-terminally processed / HRAS* / Q61411* / P01112* / HRas proto-oncogene, GTPase*  / reaction






 

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