ENSGALG00000042460


Gallus gallus
processFPGSfolylpolyglutamateligasemetabolicbiosyntheticsynthetasemursynthasefolicacid-containingcompoundtetrahydrofolylpolyglutamateactivityc-terminalcentralconservedsiteeukaryotaglutamateone-carbonmitochondrionatpbindingmetabolismfolatepterines

Features
Gene ID: ENSGALG00000042460
  
Biological name :FPGS
  
Synonyms : folylpolyglutamate synthase / FPGS
  
Possible biological names infered from orthology : Folylpolyglutamate synthase, mitochondrial / P48760 / Q05932
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 5430750
Gene end: 5434416
  
Corresponding Affymetrix probe sets: GgaAffx.3164.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047333
Ensembl peptide - ENSGALP00000063290
NCBI entrez gene - 417227     See in Manteia.
RefSeq - XM_015279710
RefSeq - XM_015279711
RefSeq - XM_015279712
RefSeq - XM_015279713
swissprot - A0A1L1RWS2
swissprot - A0A1D5P3S8
Ensembl - ENSGALG00000042460
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fpgsENSDARG00000044809Danio rerio
 FPGSENSG00000136877Homo sapiens
 FpgsENSMUSG00000009566Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001645  Folylpolyglutamate synthetase
 IPR004101  Mur ligase, C-terminal
 IPR013221  Mur ligase, central
 IPR018109  Folylpolyglutamate synthetase, conserved site
 IPR023600  Folylpolyglutamate synthase, eukaryota


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabnitrogen compound metabolic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processsmall molecule metabolismall molecule metabolic processorganic substance metaborganic substance metabolic processbiosynthetic processbiosynthetic process
ligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingdrug bindingligase activityligase activityion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingdrug bindingdrug binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006536 glutamate metabolic process IEA
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0006760 folic acid-containing compound metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0009396 folic acid-containing compound biosynthetic process IEA
 biological_processGO:0046901 tetrahydrofolylpolyglutamate biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0004326 tetrahydrofolylpolyglutamate synthase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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