ENSGALG00000042482


Gallus gallus

Features
Gene ID: ENSGALG00000042482
  
Biological name :RAB5B
  
Synonyms : RAB5B / ras-related protein Rab-5B
  
Possible biological names infered from orthology : P61020 / P61021 / RAB5B, member RAS oncogene family
  
Species: Gallus gallus
  
Chr. number: 33
Strand: 1
Band:
Gene start: 621477
Gene end: 625837
  
Corresponding Affymetrix probe sets: Gga.17824.1.S1_s_at (Chicken Array)   GgaAffx.13123.1.A1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044276
Ensembl peptide - ENSGALP00000062412
Ensembl peptide - ENSGALP00000056524
Ensembl peptide - ENSGALP00000053459
NCBI entrez gene - 100529061     See in Manteia.
RefSeq - NM_001199848
RefSeq - XM_015300271
RefSeq Peptide - NP_001186777
swissprot - A0A1L1RUB0
swissprot - A0A1D5NVA3
swissprot - A0A1D5PUC1
swissprot - A0A1D5PKU6
Ensembl - ENSGALG00000042482
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB5BENSG00000111540Homo sapiens
 Rab5bENSMUSG00000000711Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAB5C / Q98932 / Ras-related protein Rab-5C / P51148* / P35278* / RAB5C, member RAS oncogene family*ENSGALG0000000335968
RAB5A / RAB5A, member RAS oncogene family / P20339* / Q9CQD1* / Ras-related protein Rab-5A *ENSGALG0000001127268
RAB17 / RAB17, member RAS oncogene family / P35292* / Q9H0T7* / Ras-related protein Rab-17 *ENSGALG0000000389939
RAB22A / RAB22A, member RAS oncogene family / P35285* / Q9UL26*ENSGALG0000000755438
RAB31 / RAB31, member RAS oncogene family / Q13636*ENSGALG0000002287436
RAB21 / RAB21, member RAS oncogene family / P35282* / Q9UL25*ENSGALG0000001018332
RAB20 / RAB20, member RAS oncogene family / P35295* / Q9NX57* / Ras-related protein Rab-20 *ENSGALG0000001684428
Q6IMM1 / DNAJC27 / DnaJ homolog subfamily C member 27 / Q8CFP6* / Q9NZQ0* / DnaJ heat shock protein family (Hsp40) member C27*ENSGALG0000002896724


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007032 endosome organization IEA
 biological_processGO:0019882 antigen processing and presentation IEA
 biological_processGO:0030100 regulation of endocytosis IEA
 biological_processGO:0048227 plasma membrane to endosome transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
TBC/RABGAPs
Clathrin-mediated endocytosis
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000021611 Q9JM13* / Q9UJ41* / RABGEF1* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*  / complex
 ENSGALG00000006140 GGA2 / golgi associated, gamma adaptin ear containing, ARF binding protein 2 / Q6P5E6* / Q9UJY4* / ADP-ribosylation factor-binding protein GGA2 *  / complex
 ENSGALG00000039658 GGA1 / golgi associated, gamma adaptin ear containing, ARF binding protein 1 / Q8R0H9* / Q9UJY5* / ADP-ribosylation factor-binding protein GGA1 *  / complex
 ENSGALG00000039221 A6NDS4* / B9A6J9* / TBC1D3* / P0C7X1* / Q2M2D7* / Q6DHY5* / Q6IPX1* / Q8IZP1* / Q86UD7* / TBC1D3F* / TBC1D3H* / TBC1D3G* / TBC1D3I* / TBC1D3K* / TBC1D3L* / TBC1D26* / TBC1D28* / TBC1D3B* / ...  / complex / reaction






 

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