ENSGALG00000042761


Gallus gallus

Features
Gene ID: ENSGALG00000042761
  
Biological name :MUL1
  
Synonyms : mitochondrial E3 ubiquitin protein ligase 1 / MUL1
  
Possible biological names infered from orthology : Mitochondrial ubiquitin ligase activator of NFKB 1 / Q8VCM5 / Q969V5
  
Species: Gallus gallus
  
Chr. number: 21
Strand: -1
Band:
Gene start: 4886188
Gene end: 4888849
  
Corresponding Affymetrix probe sets: GgaAffx.905.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053640
NCBI entrez gene - 426969     See in Manteia.
RefSeq - XM_424579
swissprot - A0A1D5PLC4
Ensembl - ENSGALG00000042761
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mul1bENSDARG00000052527Danio rerio
 MUL1ENSG00000090432Homo sapiens
 Mul1ENSMUSG00000041241Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000000624634


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR022170  E3 Ubiquitin ligase, GIDE-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0006996 organelle organization IEA
 biological_processGO:0007257 activation of JUN kinase activity IEA
 biological_processGO:0010637 negative regulation of mitochondrial fusion IEA
 biological_processGO:0010821 regulation of mitochondrion organization IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0033235 positive regulation of protein sumoylation IEA
 biological_processGO:0045824 negative regulation of innate immune response IEA
 biological_processGO:0050689 negative regulation of defense response to virus by host IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051646 mitochondrion localization IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0060339 negative regulation of type I interferon-mediated signaling pathway IEA
 biological_processGO:0071360 cellular response to exogenous dsRNA IEA
 biological_processGO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production IEA
 biological_processGO:0090141 positive regulation of mitochondrial fission IEA
 biological_processGO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IEA
 biological_processGO:1903861 positive regulation of dendrite extension IEA
 biological_processGO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0019789 SUMO transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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