ENSGALG00000042812


Gallus gallus

Features
Gene ID: ENSGALG00000042812
  
Biological name :NRG3
  
Synonyms : neuregulin 3 / NRG3
  
Possible biological names infered from orthology : O35181 / P56975 / Pro-neuregulin-3, membrane-bound isoform Neuregulin-3
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 3440189
Gene end: 3641724
  
Corresponding Affymetrix probe sets: GgaAffx.1553.1.S1_at (Chicken Array)   GgaAffx.1570.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045972
Ensembl peptide - ENSGALP00000056702
Ensembl peptide - ENSGALP00000055203
NCBI entrez gene - 428937     See in Manteia.
RefSeq - XM_015288041
RefSeq - XM_015288042
RefSeq - XM_015288043
RefSeq - XM_015288044
swissprot - A0A1D5PQN8
swissprot - A0A1D5P001
swissprot - A0A1D5PUU5
Ensembl - ENSGALG00000042812
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nrg3bENSDARG00000089766Danio rerio
 NRG3ENSG00000185737Homo sapiens
 Nrg3ENSMUSG00000041014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRG1 / pro-neuregulin-1, membrane-bound isoform / Q02297* / neuregulin 1*ENSGALG0000001542219
NRG2 / neuregulin 2 / O14511*ENSGALG0000003364119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002154  Neuregulin, C-terminal
 IPR013032  EGF-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0021842 chemorepulsion involved in interneuron migration from the subpallium to the cortex IEA
 biological_processGO:0030879 mammary gland development IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0060596 mammary placode formation IEA
 biological_processGO:2001223 negative regulation of neuron migration IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0045499 chemorepellent activity IEA


Pathways (from Reactome)
Pathway description
Signaling by ERBB2
Signaling by ERBB4
SHC1 events in ERBB2 signaling
PI3K events in ERBB4 signaling
SHC1 events in ERBB4 signaling
PIP3 activates AKT signaling
GRB2 events in ERBB2 signaling
PI3K events in ERBB2 signaling
RAF/MAP kinase cascade
ERBB2 Regulates Cell Motility
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Downregulation of ERBB2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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