ENSMUSG00000001588


Mus musculus

Features
Gene ID: ENSMUSG00000001588
  
Biological name :Acap1
  
Synonyms : Acap1 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 / Q8K2H4
  
Possible biological names infered from orthology : Q15027
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B3
Gene start: 69881567
Gene end: 69895539
  
Corresponding Affymetrix probe sets: 10387699 (MoGene1.0st)   1434873_a_at (Mouse Genome 430 2.0 Array)   1437117_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001631
Ensembl peptide - ENSMUSP00000104262
NCBI entrez gene - 216859     See in Manteia.
MGI - MGI:2388270
RefSeq - XM_017314457
RefSeq - NM_153788
RefSeq Peptide - NP_722483
swissprot - Q8CI47
swissprot - Q8K2H4
Ensembl - ENSMUSG00000001588
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acap1ENSDARG00000056346Danio rerio
 ACAP1ENSG00000072818Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acap2 / Q6ZQK5 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 / Q15057*ENSMUSG0000004907652
Acap3 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 / Q96P50*ENSMUSG0000002903351
Asap1 / Q9QWY8 / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 / Q9ULH1* / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1*ENSMUSG0000002237723
Asap3 / Q5U464 / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 / Q8TDY4* / ArfGAP with SH3 domain, ankyrin repeat and PH domain 3*ENSMUSG0000003699523
Asap2 / Q7SIG6 / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 / O43150* / ArfGAP with SH3 domain, ankyrin repeat and PH domain 2*ENSMUSG0000005263223
Agap3 / arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform b / Q96P47* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3*ENSMUSG0000002335320
Agap2 / Q3UHD9 / Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 / Q99490* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 2*ENSMUSG0000002542220
Agap1 / Q8BXK8 / Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 / Q9UPQ3* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 1*ENSMUSG0000005501319


Protein motifs (from Interpro)
Interpro ID Name
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR027267  AH/BAR domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: A830005F24Riktm1.1(KOMP)Mbp/A830005F24Rik+
Genetic Background: C57BL/6N-A830005F24Riktm1.1(KOMP)Mbp/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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