ENSMUSG00000003623


Mus musculus
metabolicprocessCrotfattyacidactivitybeta-oxidationcarnitinetransferaseacyltransferasechoactasecotcptgenerationprecursormetabolitesenergylipidtransportcoenzymemedium-chainmitochondrionperoxisomeintracellularmembrane-boundedorganellesignalingreceptorbindingo-octanoyltransferasetransferring

Features
Gene ID: ENSMUSG00000003623
  
Biological name :Crot
  
Synonyms : Crot / Peroxisomal carnitine O-octanoyltransferase / Q9DC50
  
Possible biological names infered from orthology : carnitine O-octanoyltransferase / Q9UKG9
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: A1
Gene start: 8966033
Gene end: 8997324
  
Corresponding Affymetrix probe sets: 10528102 (MoGene1.0st)   1450966_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003720
NCBI entrez gene - 74114     See in Manteia.
MGI - MGI:1921364
RefSeq - NM_023733
RefSeq - XM_006503610
RefSeq Peptide - NP_076222
swissprot - Q9DC50
Ensembl - ENSMUSG00000003623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crotENSDARG00000040352Danio rerio
 CROTENSGALG00000008813Gallus gallus
 CROTENSG00000005469Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crat / P47934 / carnitine acetyltransferase / P43155* / carnitine O-acetyltransferase*ENSMUSG0000002685333
Cpt1a / P97742 / Carnitine O-palmitoyltransferase 1, liver isoform / P50416* / carnitine palmitoyltransferase 1A*ENSMUSG0000002490030
Cpt1c / Q8BGD5 / Mus musculus carnitine palmitoyltransferase 1c (Cpt1c), transcript variant 3, mRNA. / Q8TCG5* / carnitine palmitoyltransferase 1C*ENSMUSG0000000778329
Chat / choline O-acetyltransferase / P28329*ENSMUSG0000002191929
Cpt1b / Q924X2 / Carnitine O-palmitoyltransferase 1, muscle isoform / Q92523* / carnitine palmitoyltransferase 1B*ENSMUSG0000007893729


Protein motifs (from Interpro)
Interpro ID Name
 IPR000542  Acyltransferase ChoActase/COT/CPT


Gene Ontology (GO)
cellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processcatabolic processoxidation-reduction processnitrogen compound metabolic processmacromolecule localizationestablishment of localizationcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processsmall molecule small molecule metabolic processcatabolic procecatabolic processoxidation-reducoxidation-reduction processnitrogen compounitrogen compound metabolic processmacromolecule lmacromolecule localizationestablishment oestablishment of localization
protein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingtransferase activityprotein bindingprotein bindingtransferase activitytransferase activity
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006091 generation of precursor metabolites and energy IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process ISO
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0009437 carnitine metabolic process IDA
 biological_processGO:0015908 fatty acid transport IDA
 biological_processGO:0015936 coenzyme A metabolic process IDA
 biological_processGO:0051791 medium-chain fatty acid metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008458 carnitine O-octanoyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of pristanoyl-CoA
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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