ENSMUSG00000005510


Mus musculus

Features
Gene ID: ENSMUSG00000005510
  
Biological name :Ndufs3
  
Synonyms : NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial / Ndufs3 / Q9DCT2
  
Possible biological names infered from orthology : NADH:ubiquinone oxidoreductase core subunit S3 / O75489
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E1
Gene start: 90894634
Gene end: 90904827
  
Corresponding Affymetrix probe sets: 10386171 (MoGene1.0st)   10484912 (MoGene1.0st)   1423737_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000005647
NCBI entrez gene - 68349     See in Manteia.
MGI - MGI:1915599
RefSeq - NM_026688
RefSeq Peptide - NP_080964
swissprot - Q9DCT2
Ensembl - ENSMUSG00000005510
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufs3ENSDARG00000015385Danio rerio
 NDUFS3ENSGALG00000008084Gallus gallus
 NDUFS3ENSG00000213619Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001268  NADH:ubiquinone oxidoreductase, 30kDa subunit
 IPR010218  NADH dehydrogenase, subunit C
 IPR020396  NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site
 IPR037232  NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0045333 cellular respiration IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0003954 NADH dehydrogenase activity ISO
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016651 oxidoreductase activity, acting on NAD(P)H IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001391 abnormal tail movements "a change from the normal manner of moving the tail" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Myoz1tm1a(EUCOMM)Hmgu/Myoz1tm1a(EUCOMM)Hmgu
Genetic Background: Not Specified

 MP:0002833 increased heart weight "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Myo5atm1a(KOMP)Wtsi/Myo5atm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Myo5atm1a(KOMP)Wtsi/Wtsi

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myo5atm1a(KOMP)Wtsi/Myo5atm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Myo5atm1a(KOMP)Wtsi/Wtsi

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Myo5atm1a(KOMP)Wtsi/Myo5atm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Myo5atm1a(KOMP)Wtsi/Wtsi

 MP:0005571 decreased lactate dehydrogenase level "less than the normal concentration of this enzyme, which catalyzes the interconversion of lactate and pyruvate" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Myo5atm1a(KOMP)Wtsi/Myo5atm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Myo5atm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr