| MP:0000162 | lordosis | "anteriorly convex curvature of the spine, "saddle back" " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62022] |
Show
Allelic Composition: Lhx2tm1.1Lcar/Lhx2tm1.1Lcar,Tg(Lhx2-cre)1Lcar/0
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000371 | diluted coat color | "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
Allelic Composition: Hps1ep/Hps1ep,Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6 Hps1ep
|
| MP:0000410 | waved hair | "hair or fur having undulations or a sinusoidal shape" [J:47620] |
Show
Allelic Composition: Lhx2tm1.1Lcar/Lhx2tm1.1Lcar,Tg(Lhx2-cre)1Lcar/0
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001175 | abnormal lung morphology | "malformed organ of respiration" [J:35802] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0001177 | atelectasis | "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa,Tgm3we/Tgm3we-Bkr
Genetic Background: involves: 129 * C57BL/10 * UW
|
| MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0001393 | ataxia | "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
Show
Allelic Composition: Lhx2tm1.1Lcar/Lhx2tm1.1Lcar,Tg(Lhx2-cre)1Lcar/0
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001510 | abnormal coat appearance | "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lhx2tm1.1Lcar/Lhx2tm1.1Lcar,Tg(Lhx2-cre)1Lcar/0
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001522 | impaired swimming | "reduced ability or inability to swim" [J:45446, J:39081] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0001525 | impaired balance | "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0001533 | abnormal skeleton physiology | "anomalous function of the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lhx2tm1.1Lcar/Lhx2tm1.1Lcar,Tg(Lhx2-cre)1Lcar/0
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0001613 | abnormal vasodilation | "anomalous widening of the lumen of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: F11tm1Gjb/F11tm1Gjb
Genetic Background: B6.129X1-F11tm1Gjb
|
| MP:0001760 | abnormal urine enzyme level | "any change in the level of excretion of enzymes in the urine" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0001861 | lung inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0001942 | abnormal lung volume | "anomaly in the amount of air that the lungs contain at various points of the respiratory cycle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0001958 | emphysema | "lung disease characterized by increased size of terminal bronchioles with destructive changes in their walls and reduction in number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33629] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0002113 | abnormal skeleton development | "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lhx2tm1.1Lcar/Lhx2tm1.1Lcar,Tg(Lhx2-cre)1Lcar/0
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002133 | abnormal respiratory system physiology | "anomalous function of the pulmonary system; inability or reduced ability to intake and exchange oxygen and carbon dioxide with the environment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0002136 | abnormal kidney physiology | "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0002270 | abnormal alveoli morphology | "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0002276 | abnormal lung interstitium morphology | "any structural anomaly of the lung tissue, but not including the conducting airways (bronchi, bronchioles, alveoli) " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0002314 | abnormal respiratory mechanics | "anomaly in the action of the lungs, diaphragm, ribs and chest wall during respiration" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0002826 | tonic seizures | "increased number or decreased threshold for the induction of a seizure characterized by muscle rigidity" [hdene:Howard Dene , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0002894 | abnormal otoliths | "malformed crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa,Tgm3we/Tgm3we-Bkr
Genetic Background: involves: 129 * C57BL/10 * UW
|
| MP:0003172 | abnormal lysosome physiology | "ability of lysosomes to produce enzymes necessary for digestion of exogenous material is impaired" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0003641 | small lung | "reduced size of the lung relative to normal" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95332] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa,Tgm3we/Tgm3we-Bkr
Genetic Background: involves: 129 * C57BL/10 * UW
|
| MP:0003718 | maternal effect | "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Edaraddcr/Edaraddcr
Genetic Background: involves: C57BL/6J
|
| MP:0003828 | pulmonary edema | "an accumulation of an excessive amount of watery fluid in the lung " [J:44108, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0004003 | abnormal vascular endothelial cell physiology | "anomaly in the function of the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: F11tm1Gjb/F11tm1Gjb
Genetic Background: B6.129X1-F11tm1Gjb
|
| MP:0004703 | abnormal vertebral column | "any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa,Tgm3we/Tgm3we-Bkr
Genetic Background: involves: 129 * C57BL/10 * UW
|
| MP:0004725 | decreased platelet serotonin level | "reduced concentration of serotonin in the platelets; this biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0004812 | abnormal linear vestibular evoked potential | "anomaly in the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head); normally, this response is measured by electrophysiological activity of the peripheral vestibular nerve; this assesses the function of the gravity receptor system including the utricles and saccules of the inner ear" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0005075 | abnormal melanosome morphology | "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0005172 | lack of eye pigmentation | "visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
Show
Allelic Composition: Wnt3atm1Amc/Wnt3atm1Amc
Genetic Background: involves: 129S1/Sv * C57BL/6J
|
| MP:0005191 | head tilt | "condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0005464 | abnormal platelet physiology | "atypical response of the non-nucleated cells found in the blood and involved in blood coagulation" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0005606 | increased bleeding time | "greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0006159 | ocular albinism | "absence of melanin production in the eye only" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0006298 | abnormal platelet activation | "anomaly in the series of progressive, overlapping events triggered by exposure of platelets to signals from subendothelial tissue, including shape change, adhesiveness, aggregation, and release reactions; when carried through to completion, these events lead to the formation of a stable hemostatic plug" [GO:0030168, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0009448 | decreased platelet ATP level | "reduced concentration of the major energy source adenosine triphosphate produced by dense bodies located in platelets" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0009549 | impaired platelet aggregation | "decrease in the ability of one platelet to one or more other platelets via adhesion molecules" [GO:0070527] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0009557 | decreased platelet ADP level | "reduced concentration of the major energy source adenosine diphosphate produced by dense bodies located in platelets" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0009642 | abnormal blood homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0010099 | abnormal thoracic cage shape | "anomaly in the overall regular dome shape of the ribcage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa,Tgm3we/Tgm3we-Bkr
Genetic Background: involves: 129 * C57BL/10 * UW
|
| MP:0010192 | abnormal retinal melanin granule morphology | "any structural anomaly of the pigment particles in the retina" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"] |
Show
Allelic Composition: a/a,Myo5ad/Myo5ad
Genetic Background: involves: DBA/2J
|
| MP:0010766 | abnormal NK cell physiology | "any functional anomaly of a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells" [GOC:add, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:15771571] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0010898 | abnormal pulmonary alveolus epithelium morphology | "any structural anomaly of the epithelial layer of the alveoli" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
| MP:0011400 | complete lethality | "all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa,Tgm3we/Tgm3we-Bkr
Genetic Background: involves: 129 * C57BL/10 * UW
|
| MP:0020432 | decreased platelet dense granule number | "decreased number of the electron-dense bodies occurring in blood platelets that store and secrete adenosine nucleotides and serotonin" [orcid.org/0000-0003-4606-0597] |
Show
Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J
|
