ENSMUSG00000006476


Mus musculus

Features
Gene ID: ENSMUSG00000006476
  
Biological name :Nsmf
  
Synonyms : NMDA receptor synaptonuclear signaling and neuronal migration factor / Nsmf / Q99NF2
  
Possible biological names infered from orthology : Q6X4W1
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A3
Gene start: 25054355
Gene end: 25062881
  
Corresponding Affymetrix probe sets: 10469906 (MoGene1.0st)   1436959_x_at (Mouse Genome 430 2.0 Array)   1439398_x_at (Mouse Genome 430 2.0 Array)   1442706_at (Mouse Genome 430 2.0 Array)   1449474_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110028
Ensembl peptide - ENSMUSP00000110030
Ensembl peptide - ENSMUSP00000141583
Ensembl peptide - ENSMUSP00000141410
Ensembl peptide - ENSMUSP00000121580
Ensembl peptide - ENSMUSP00000120376
Ensembl peptide - ENSMUSP00000116106
Ensembl peptide - ENSMUSP00000112273
Ensembl peptide - ENSMUSP00000006646
Ensembl peptide - ENSMUSP00000074022
Ensembl peptide - ENSMUSP00000097908
Ensembl peptide - ENSMUSP00000099995
NCBI entrez gene - 56876     See in Manteia.
MGI - MGI:1861755
RefSeq - XM_006498201
RefSeq - XM_017319144
RefSeq - XM_017319143
RefSeq - XM_017319142
RefSeq - XM_006498200
RefSeq - XM_017319141
RefSeq - XM_017319140
RefSeq - XM_006498203
RefSeq - XM_006498202
RefSeq - NM_001039386
RefSeq - NM_001039387
RefSeq - NM_001177654
RefSeq - NM_001177655
RefSeq - NM_020276
RefSeq - XM_017319145
RefSeq Peptide - NP_001034476
RefSeq Peptide - NP_001034475
RefSeq Peptide - NP_001171125
RefSeq Peptide - NP_001171126
RefSeq Peptide - NP_064672
swissprot - Q99NF2
swissprot - A2AJ96
swissprot - A0A0A6YW62
swissprot - F6VTS9
swissprot - F6TKU5
swissprot - A0A0A6YWK2
swissprot - A2AJ90
swissprot - A2AJ91
swissprot - A2AJ92
swissprot - A2AJ95
Ensembl - ENSMUSG00000006476
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nsmfaENSDARG00000060025Danio rerio
 nsmfbENSDARG00000101234Danio rerio
 NSMFENSGALG00000008681Gallus gallus
 NSMFENSG00000165802Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR033374  NMDA receptor synaptonuclear signalling and neuronal migration factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035307 positive regulation of protein dephosphorylation ISS
 biological_processGO:0043523 regulation of neuron apoptotic process ISS
 biological_processGO:0048168 regulation of neuronal synaptic plasticity IEA
 biological_processGO:0048814 regulation of dendrite morphogenesis ISS
 biological_processGO:0071230 cellular response to amino acid stimulus ISS
 biological_processGO:0071257 cellular response to electrical stimulus ISS
 biological_processGO:0071371 cellular response to gonadotropin stimulus IDA
 biological_processGO:2001222 regulation of neuron migration IEA
 biological_processGO:2001224 positive regulation of neuron migration ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005635 nuclear envelope ISS
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005719 nuclear euchromatin ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0016363 nuclear matrix ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0030863 cortical cytoskeleton ISS
 cellular_componentGO:0031965 nuclear membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0045202 synapse ISS
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0097440 apical dendrite ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

Allelic Composition: Nsmftm1a(KOMP)Wtsi/Nsmf+
Genetic Background: involves: C57BL/6N

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

Allelic Composition: Nsmftm1a(KOMP)Wtsi/Nsmf+
Genetic Background: involves: C57BL/6N

 MP:0001938 delayed sexual maturation "immaturity of the sexual organs at a given age" [J:61190]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

 MP:0002636 delayed vaginal opening "the opening of the genital canal in a female occuring at a later than expected age" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

 MP:0004856 decreased ovary weight "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

 MP:0004905 decreased uterus weight "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Myo5atm1a(KOMP)Wtsi/Myo5atm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Myo5atm1a(KOMP)Wtsi/Wtsi

 MP:0008335 decreased gonadotroph cell number "reduced number of the anterior pituitary cells that can produce both follicle stimulating hormone (FSH) and luteinizing hormone (LH)" [MESH:A06.407.747.608.750]
Show

Allelic Composition: Hrhr/Hrhr,Tg(CD2-Stat6*V625A*T626A)78Mhk/0
Genetic Background: involves: C3H * SKH1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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